Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26941636 | 0.98 | MAPT (0.39) | ALDH1A1MAPTSMN1; SMN2OPRM1L3MBTL1 | |
| SCHEMBL26941610 | 0.88 | MAPK1 (0.36) | ALDH1A1MAPTSMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL26941611 | 0.88 | ALDH1A1 (0.37) | ALDH1A1MAPTSMN1; SMN2LMNADRD3 | |
| SCHEMBL26941574 | 0.88 | OPRM1 (0.35) | ALDH1A1MAPTSMN1; SMN2OPRM1TDP1 | |
| SCHEMBL26941643 | 0.87 | OPRM1 (0.34) | ALDH1A1MAPTSMN1; SMN2OPRM1L3MBTL1 | |
| SCHEMBL26941571 | 0.86 | OPRM1 (0.36) | ALDH1A1MAPTSMN1; SMN2OPRM1L3MBTL1 | |
| SCHEMBL24393970 | 0.85 | ALDH1A1 (0.39) | ALDH1A1MAPTSMN1; SMN2OPRM1L3MBTL1 | |
| SCHEMBL26942730 | 0.85 | PPARD (0.36) | MAPTLMNAPTGDR2 | |
| SCHEMBL24394153 | 0.85 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2HSD11B1MEN1KMT2A | |
| SCHEMBL26929241 | 0.85 | PDE2A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230399289-A1 | ITACONIC ACID DERIVATIVES | SITRYX THERAPEUTICS LIMITED (GB) | 2023-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230399289-A1 | ITACONIC ACID DERIVATIVES | IL1R1, LRBA, HCAR1 | ALDH1A1 28/4885MAPT 3634/4885SMN1; SMN2 3304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.