Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26944359 | 0.92 | KDM4E (0.49) | HRH3ALDH1A1KDM4EPKMCXCR4 | |
| SCHEMBL16463859 | 0.84 | KDM4E (0.43) | HRH3ALDH1A1KDM4EPKMCXCR4 | |
| SCHEMBL2584901 | 0.81 | POLB (0.58) | HRH3ALDH1A1KDM4EPKMCXCR4 | |
| SCHEMBL24079946 | 0.80 | KDM1A (0.55) | HRH3ALDH1A1KDM4EPKMCXCR4 | |
| SCHEMBL4736629 | 0.79 | POLB (0.60) | HRH3ALDH1A1KDM4EPKMCXCR4 | |
| SCHEMBL10953965 | 0.78 | HRH3 (0.88) | HRH3ALDH1A1KDM4EPKMCXCR4 | |
| SCHEMBL5864236 | 0.78 | HRH3 (0.72) | HRH3ALDH1A1KDM4ECXCR4POLB | |
| SCHEMBL11434269 | 0.75 | HRH3 (0.69) | HRH3ALDH1A1KDM4EPKMCXCR4 | |
| SCHEMBL9417582 | 0.75 | ALDH1A1 (0.94) | HRH3ALDH1A1KDM4EPKMPOLB | |
| SCHEMBL3686059 | 0.75 | ALDH1A1 (0.94) | HRH3ALDH1A1KDM4EPKMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023235925-A1 | COMPOUNDS WITH MERTK ACTIVITY | MONASH UNIVERSITY (AU) | 2023-12-14 | — | — | WO | disclosed |