Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2270360 | 0.80 | CHRM2 (0.38) | FFAR3OPRM1 | |
| SCHEMBL15759336 | 0.75 | FFAR3 (0.38) | FFAR3OPRM1 | |
| SCHEMBL879708 | 0.75 | OPRM1 (0.31) | OPRM1 | |
| SCHEMBL1966250 | 0.74 | GAA (0.34) | — | |
| SCHEMBL8513076 | 0.74 | SPR (0.30) | — | |
| SCHEMBL1427523 | 0.73 | GRM3 (0.38) | FFAR3OPRM1 | |
| SCHEMBL345818 | 0.72 | FFAR3 (0.37) | FFAR3OPRM1 | |
| SCHEMBL17163840 | 0.72 | KDM1A (0.36) | FFAR3OPRM1 | |
| SCHEMBL17163833 | 0.72 | KDM1A (0.36) | FFAR3OPRM1 | |
| SCHEMBL17163838 | 0.72 | KDM1A (0.36) | FFAR3OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8859608-B2 | Spiro amino compounds suitable for the treatment of inter alia sleep disorders and drug addiction | ROTTAPHARM BIOTECH S.R.L. (IT) | 2014-10-14 | — | — | US | disclosed |
| US-20120115882-A1 | SPIRO AMINO COMPOUNDS SUITABLE FOR THE TREATMENT OF INTER ALIA SLEEP DISORDERS AND DRUG ADDICTION | ROTTAPHARM BIOTECH S.R.L. (IT) | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120115882-A1 | SPIRO AMINO COMPOUNDS SUITABLE FOR THE TREATMENT OF INTER ALIA SLEEP DISORDERS AND DRUG ADDICTION | SLC1A1, SLC6A3, SLC1A2 | FFAR3 3556/4885OPRM1 77/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.