SCHEMBL26948627

SCHEMBL26948627

CC(C)N1CCC(CN2CCN(C(C)C)CC2(C)C)CC1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 3/20 0.34
KCNH2 Q12809 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26949618 0.82 HRH3 (0.36) HRH3KCNH2
SCHEMBL24671512 0.79 HRH3 (0.36) HRH3KCNH2
SCHEMBL7907972 0.74 CHRM1 (0.35)
SCHEMBL24250661 0.73 PIK3CD (0.31)
SCHEMBL14453909 0.72 CHRM5 (0.41) HRH3KCNH2
SCHEMBL25726059 0.71 SLC6A2 (0.33)
SCHEMBL13860741 0.71 CHRM5 (0.50) HRH3KCNH2
SCHEMBL24233173 0.71 ACHE (0.44) HRH3KCNH2
SCHEMBL26948972 0.70 CHRM5 (0.45) HRH3KCNH2
SCHEMBL22520769 0.70 CHRM5 (0.43) HRH3KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023240038-A1 TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS Treeline Biosciences, Inc. (US) 2023-12-14 WO disclosed