Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 17/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL269267 | 0.86 | PTPN1 (0.44) | PTPN1ACHE | |
| SCHEMBL263313 | 0.86 | PTPN1 (0.59) | PTPN1HSD11B1 | |
| SCHEMBL1842933 | 0.86 | PTPN1 (0.59) | PTPN1HSD11B1 | |
| SCHEMBL264109 | 0.82 | CYP17A1 (0.50) | PTPN1HSD11B1 | |
| SCHEMBL284052 | 0.82 | HSD11B1 (0.42) | PTPN1HSD11B1 | |
| SCHEMBL269659 | 0.82 | ACHE (0.46) | PTPN1ACHE | |
| SCHEMBL16722810 | 0.81 | CES2 (0.46) | PTPN1 | |
| SCHEMBL269137 | 0.81 | PTPN1 (0.40) | PTPN1ACHE | |
| SCHEMBL29722835 | 0.76 | PTPN1 (0.53) | PTPN1HSD11B1 | |
| SCHEMBL20507035 | 0.76 | MEN1 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8134004-B2 | Substituted N-bicyclicalkyl bicycliccarboxyamide compounds | PFIZER INC. (US) | 2012-03-13 | — | — | US | disclosed |
| US-20090253740-A1 | SUBSTITUTED N-BICYCLICALKYL BICYCLICCARBOXYAMIDE COMPOUNDS | PFIZER INC | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253740-A1 | SUBSTITUTED N-BICYCLICALKYL BICYCLICCARBOXYAMIDE COMPOUNDS | OPRL1, CNR1, TRPV1 | PTPN1 2258/4885HSD11B1 2187/4885ACHE 1793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.