Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 8/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 2/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26923618 | 0.83 | PARP10 (0.39) | PARP10PARP11CYP11B2CYP11B1CYP17A1 | |
| SCHEMBL26948394 | 0.80 | PARP10 (0.43) | PARP10PARP11CYP11B2CYP11B1CYP17A1 | |
| SCHEMBL27018669 | 0.78 | PARP10 (0.45) | PARP10PARP11CYP11B2CYP11B1CYP17A1 | |
| SCHEMBL23249804 | 0.76 | PARP10 (0.43) | PARP10PARP11CYP11B2CYP11B1CYP17A1 | |
| SCHEMBL29890183 | 0.76 | PARP10 (0.43) | PARP10PARP11CYP11B2CYP11B1CYP17A1 | |
| SCHEMBL26950329 | 0.74 | CYP11B1 (0.57) | PARP10PARP11CYP11B2CYP11B1PRMT5 | |
| SCHEMBL9720728 | 0.73 | MAOA (0.44) | SRC | |
| SCHEMBL12947928 | 0.72 | CYP11B2 (0.50) | PARP10PARP11CYP11B2CYP11B1HDAC1 | |
| SCHEMBL3094265 | 0.71 | PTGDR2 (0.50) | CYP3A4 | |
| SCHEMBL28760897 | 0.68 | TDO2 (0.48) | CYP11B2CYP11B1TDO2PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023240084-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | DENALI THERAPEUTICS INC. (US) | 2023-12-14 | — | — | WO | disclosed |