Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGK1 | O00141 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 2/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | CDK9 | P50750 | 1/20 | 0.45 |
| ▸ | LYN | P07948 | 2/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
| ▸ | CHUK | O15111 | 1/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | CLK1 | P49759 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.43 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.42 |
| ▸ | FYN | P06241 | 2/20 | 0.41 |
| ▸ | CSF1R | P07333 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31735072 | 1.00 | SGK1 (0.46) | SGK1CDK2CCNT1CCNA2CDK9 | |
| SCHEMBL26953245 | 0.85 | CDK2 (0.53) | SGK1CDK2CCNT1CCNA2CDK9 | |
| SCHEMBL31734958 | 0.85 | CDK2 (0.53) | SGK1CDK2CCNT1CCNA2CDK9 | |
| SCHEMBL26953278 | 0.84 | SGK1 (0.57) | SGK1CDK2CDK9LYNIKBKB | |
| SCHEMBL31735012 | 0.84 | SGK1 (0.57) | SGK1CDK2CDK9LYNIKBKB | |
| SCHEMBL31734890 | 0.83 | LRRK2 (0.59) | SGK1IGF1RLRRK2FYN | |
| SCHEMBL31735005 | 0.83 | LRRK2 (0.59) | SGK1CDK2CCNT1CCNA2CDK9 | |
| SCHEMBL26953145 | 0.83 | LRRK2 (0.59) | SGK1IGF1RLRRK2FYN | |
| SCHEMBL26953170 | 0.83 | LRRK2 (0.59) | SGK1CDK2CCNT1CCNA2CDK9 | |
| SCHEMBL31735137 | 0.81 | LRRK2 (0.45) | SGK1CDK2CCNT1CCNA2CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023239727-A1 | LATS INHIBITORS AND USES THEREOF | THE USA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2023-12-14 | — | — | WO | disclosed |