Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.55 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.52 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.52 |
| ▸ | CDC42BPB | Q9Y5S2 | 3/20 | 0.52 |
| ▸ | CDC42BPA | Q5VT25 | 2/20 | 0.51 |
| ▸ | SGK1 | O00141 | 1/20 | 0.50 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | VHL | P40337 | 1/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | CCNK | O75909 | 1/20 | 0.44 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31734861 | 1.00 | CYP2A6 (0.55) | CYP2A6ROCK2ROCK1CDC42BPBCDC42BPA | |
| SCHEMBL26953278 | 0.90 | SGK1 (0.57) | CYP2A6ROCK2ROCK1CDC42BPASGK1 | |
| SCHEMBL31735012 | 0.90 | SGK1 (0.57) | CYP2A6ROCK2ROCK1CDC42BPASGK1 | |
| SCHEMBL26953219 | 0.83 | LRRK2 (0.45) | ROCK2ROCK1CDC42BPASGK1LRRK2 | |
| SCHEMBL31735137 | 0.83 | LRRK2 (0.45) | ROCK2ROCK1CDC42BPASGK1LRRK2 | |
| SCHEMBL31734890 | 0.83 | LRRK2 (0.59) | SGK1LRRK2NUDT1STK3 | |
| SCHEMBL31734958 | 0.83 | CDK2 (0.53) | ROCK2SGK1LRRK2JAK3CDC7 | |
| SCHEMBL31735005 | 0.83 | LRRK2 (0.59) | SGK1LRRK2JAK3CDK2CDK9 | |
| SCHEMBL26953170 | 0.83 | LRRK2 (0.59) | SGK1LRRK2JAK3CDK2CDK9 | |
| SCHEMBL26953245 | 0.83 | CDK2 (0.53) | ROCK2SGK1LRRK2JAK3CDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023239727-A1 | LATS INHIBITORS AND USES THEREOF | THE USA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2023-12-14 | — | — | WO | disclosed |