Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | DGKA | P23743 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6153346 | 0.87 | ALDH1A1 (0.52) | NAAADGKAALDH1A1MAPTATM | |
| SCHEMBL27502960 | 0.84 | KDM4E (0.50) | NAAADGKAALDH1A1MAPTATM | |
| SCHEMBL9742722 | 0.83 | NAAA (0.48) | NAAADGKAALDH1A1MAPTATM | |
| SCHEMBL16321096 | 0.83 | NAAA (0.42) | NAAADGKAALDH1A1MAPTATM | |
| SCHEMBL95383 | 0.83 | ALDH1A1 (0.52) | NAAADGKAALDH1A1MAPTATM | |
| SCHEMBL1866046 | 0.83 | ALDH1A1 (0.52) | NAAADGKAALDH1A1MAPTATM | |
| SCHEMBL8652868 | 0.81 | CYP19A1 (0.42) | ALDH1A1MAPK1L3MBTL1KDM4EKMT2A | |
| SCHEMBL19837599 | 0.81 | GPR84 (0.48) | NAAADGKAALDH1A1MAPTATM | |
| SCHEMBL8862337 | 0.81 | NAAA (0.47) | NAAADGKAALDH1A1MAPTATM | |
| SCHEMBL6154556 | 0.81 | NAAA (0.61) | NAAADGKAALDH1A1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168828-B2 | Process for the preparation of pregabalin | MSN LABORATORIES, LIMITED (IN) | 2012-05-01 | — | — | US | disclosed |
| US-20100179345-A1 | NOVEL PROCESS FOR THE PREPARATION OF PREGABALIN | MSN LABORATORIES, LIMITED (IN) | 2010-07-15 | — | — | US | disclosed |
| EP-2170813-A2 | A NOVEL PROCESS FOR THE PREPARATION OF PREGABALIN | Satyanarayana Reddy, Manne (IN) | 2010-04-07 | — | — | EP | disclosed |
| WO-2009001372-A2 | A NOVEL PROCESS FOR THE PREPARATION OF PREGABALIN | SATYANARAYANA REDDY MANNE (IN) | 2008-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100179345-A1 | NOVEL PROCESS FOR THE PREPARATION OF PREGABALIN | GAP43, RIMKLA, GABRE | NAAA 443/4885DGKA 1886/4885ALDH1A1 1323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.