SCHEMBL269577

SCHEMBL269577

COc1ccc(C(=O)CC(=O)c2cc(C(C)C)ccc2C)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 6/20 0.52
KMT2A Q03164 7/20 0.52
MEN1 O00255 6/20 0.52
RAB9A P51151 6/20 0.52
ALDH1A1 P00352 4/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
POLB P06746 1/20 0.49
HSD17B10 Q99714 3/20 0.49
LMNA P02545 3/20 0.49
ALOX15 P16050 2/20 0.49
APEX1 P27695 1/20 0.49
MAPK1 P28482 1/20 0.49
RECQL P46063 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
MAPT P10636 4/20 0.48
KDM4E B2RXH2 2/20 0.48
TP53 P04637 2/20 0.48
ALOX12 P18054 2/20 0.48
USP2 O75604 1/20 0.48
HTT P42858 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3795638 0.91 ALDH1A1 (0.60) NPC1KMT2AMEN1RAB9AALDH1A1
SCHEMBL4743751 0.84 MEN1 (0.68) NPC1KMT2AMEN1RAB9AALDH1A1
SCHEMBL10932866 0.83 NPC1 (0.64) NPC1KMT2AMEN1RAB9AALDH1A1
SCHEMBL6130576 0.82 LMNA (0.48) NPC1KMT2AMEN1RAB9AALDH1A1
SCHEMBL5306428 0.80 ALDH1A1 (0.52) NPC1KMT2AMEN1RAB9AALDH1A1
SCHEMBL269013 0.79 LMNA (0.72) NPC1KMT2AMEN1RAB9AALDH1A1
SCHEMBL268888 0.76 NPC1 (0.70) NPC1KMT2AMEN1RAB9AALDH1A1
SCHEMBL153386 0.76 ALDH1A1 (0.76) NPC1KMT2AALDH1A1HSD17B10LMNA
SCHEMBL7832117 0.76 NPC1 (0.58) NPC1KMT2AMEN1RAB9AALDH1A1
SCHEMBL15080783 0.75 MAPT (0.56) NPC1KMT2AMEN1RAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1496 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4395733-A1 A PHOTOPROTECTIVE PERSONAL CARE COMPOSITION Unilever IP Holdings B.V. (NL) 2024-07-10 EP claimed
US-20240173235-A1 PERSONAL CARE COMPOSITIONS COMPRISING SILAHYDROCARBONS MOMENTIVE PERFORMANCE MATERIALS INC. 2024-05-30 US claimed
EP-4322915-A1 PERSONAL CARE COMPOSITIONS COMPRISING SILAHYDROCARBONS Momentive Performance Materials Inc. (US) 2024-02-21 EP claimed
WO-2023110777-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND PENTAERYTHRITYL TETRA-DI-T-BUTYL HYDROXYHYDROCINNAMATE L'OREAL (FR) 2023-06-22 WO claimed
WO-2023030963-A1 A PHOTOPROTECTIVE PERSONAL CARE COMPOSITION UNILEVER IP HOLDINGS B.V. (NL) 2023-03-09 WO claimed
US-20220226215-A1 PHOTOPROTECTIVE COMPOSITIONS COMPRISING A DIBENZOYLMETHANE DERIVATIVE, A MEROCYANINE COMPOUND AND A COMPOUND CAPABLE OF ACCEPTING THE TRIPLET EXCITED LEVEL ENERGY OF THE DIBENZOYLMETHANE COMPOUND L'OREAL (FR) 2022-07-21 US claimed
US-20210106509-A1 A sunscreen composition CONOPCO, INC., D/B/A UNILEVER (US) 2021-04-15 US claimed
US-10952944-B2 Cyclocarboxylic acid containing personal care compositions CONOPCO, INC. (US) 2021-03-23 US claimed
EP-3784355-A1 A SUNSCREEN COMPOSITION Unilever N.V. (NL) 2021-03-03 EP claimed
EP-3357483-B1 SUNSCREEN COSMETIC SHISEIDO CO LTD (JP) 2021-01-27 EP claimed
EP-0717982-B1 Process for photostabilizing of dibenzoylmethan derivatives of sunscreen agent, the photostable cosmetic sunscreen compositions and their use OREAL (FR) 1997-07-23 EP claimed
EP-0780119-A1 Light screening compositions GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) 1997-06-25 EP claimed
EP-0754445-A2 Photostable cosmetic light screening compositions GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) 1997-01-22 EP claimed
US-5587150-A Photostable cosmetic screening composition containing a UV-A screening agent and an alkyl β, β-diphenylacrylate or α-cyano-β,β-diphenylacrylate L'OREAL (FR) 1996-12-24 US claimed
EP-0748624-A1 Composition containing a dibenzoylmethane derivative and a nanopigment of titanium dioxide and uses thereof L'OREAL (FR) 1996-12-18 EP claimed
US-5576354-A Photostable cosmetic screening composition containing a UV-A screening agent and an alkyl β, β-diphenylacrylate or α-cyano-β,β-diphenylacrylate L'OREAL (FR) 1996-11-19 US claimed
EP-0717982-A1 Process for photostabilizing of dibenzoylmethan derivatives of sunscreen agent, the photostable cosmetic sunscreen compositions and their use L'OREAL (FR) 1996-06-26 EP claimed
EP-0709080-A1 Photostable cosmetic light screening compositions GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) 1996-05-01 EP claimed
EP-0514491-B1 LIGHT-RESISTANT FILTERING COSMETIC COMPOSITION CONTAINING A UV-A FILTER AND AN ALKYL BETA, BETA-DIPHENYLACRYLATE OR AN ALKYL ALPHA-CYANO-BETA, BETA-DIPHENYLACRYLATE OREAL (FR) 1993-11-03 EP claimed
WO-1991011989-A1 LIGHT-RESISTANT FILTERING COSMETIC COMPOSITION CONTAINING A UV-A FILTER AND AN ALKYL β, β-DIPHENYLACRYLATE OR AN ALKYL α-CYANO-β, β-DIPHENYLACRYLATE L'OREAL (FR) 1991-08-22 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10952944-B2 Cyclocarboxylic acid containing personal care compositions ERCC1, C1R, COL1A1 NPC1 2952/4885KMT2A 4200/4885MEN1 980/4885
US-20220226215-A1 PHOTOPROTECTIVE COMPOSITIONS COMPRISING A DIBENZOYLMETHANE DERIVATIVE, A MEROCYANINE COMPOUND AND A COMPOUND CAPABLE OF ACCEPTING THE TRIPLET EXCITED LEVEL ENERGY OF THE DIBENZOYLMETHANE COMPOUND ERCC5, DDT, ERCC1 NPC1 2067/4885KMT2A 3034/4885MEN1 180/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.