Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 5/20 | 0.46 |
| ▸ | MAOB | P27338 | 5/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP2 | O95551 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13011509 | 0.84 | CNR2 (0.60) | CYP2D6CSNK2A1CNR2PARP1ALDH1A1 | |
| SCHEMBL16377332 | 0.81 | CSNK2A1 (0.62) | CYP2D6CSNK2A1CSNK2A2CSNK2BPARP1 | |
| SCHEMBL26966717 | 0.80 | CSNK2A2 (0.47) | CYP2D6CSNK2A1CSNK2A2CSNK2BPARP1 | |
| SCHEMBL30686839 | 0.80 | CSNK2A2 (0.47) | CYP2D6CSNK2A1CSNK2A2CSNK2BPARP1 | |
| SCHEMBL26966711 | 0.79 | KDM4E (0.60) | CSNK2A1CSNK2A2CSNK2BPARP1ROCK2 | |
| SCHEMBL27175650 | 0.77 | CNR2 (0.70) | CYP2D6CNR2ALDH1A1HPGDPTGER4 | |
| SCHEMBL26966716 | 0.74 | SRC (0.54) | CSNK2A1CSNK2A2CSNK2BCNR2 | |
| SCHEMBL30686840 | 0.74 | SRC (0.54) | CSNK2A1CSNK2A2CSNK2BCNR2 | |
| SCHEMBL16345008 | 0.73 | ROCK2 (0.62) | CSNK2A1PARP1ROCK2PTGER4TUBB4A | |
| SCHEMBL18941207 | 0.72 | RAD52 (0.61) | CSNK2A1CNR2ALDH1A1HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11851430-B1 | Pyrido[4,3-B]indole-7-carboxylic acid compounds as CK2 inhibitors | King Faisal University (SA) | 2023-12-26 | — | — | US | claimed |
| US-11851430-B1 | Pyrido[4,3-B]indole-7-carboxylic acid compounds as CK2 inhibitors | King Faisal University (SA) | 2023-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11851430-B1 | Pyrido[4,3-B]indole-7-carboxylic acid compounds as CK2 inhibitors | CSNK2A3, CSNK2A1, CSNK2A2 | CYP2D6 1763/4885CSNK2A1 2/4885CSNK2A2 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.