SCHEMBL26966752

SCHEMBL26966752

O=C(O)CN(CCOCCN(CC(=O)O)Cc1cccc(C(=O)O)n1)Cc1cccc(C(=O)O)n1

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
BLM P54132 1/20 0.46
PMP22 Q01453 1/20 0.46
HSD17B10 Q99714 1/20 0.46
KDM4E B2RXH2 2/20 0.42
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42
ACMSD Q8TDX5 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
MRGPRX4 Q96LA9 4/20 0.42
CA1 P00915 10/20 0.39
CA2 P00918 10/20 0.39
PPARG P37231 1/20 0.36
PPARA Q07869 1/20 0.36
LMNA P02545 1/20 0.36
PTGER1 P34995 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24722607 0.96 BLM (0.49) BLMPMP22HSD17B10KDM4EALOX15
SCHEMBL24722998 0.91 BLM (0.38) BLMPMP22HSD17B10KDM4EALOX15
SCHEMBL2349945 0.90 KDM4E (0.48) BLMPMP22KDM4EALOX15TSHR
SCHEMBL29892650 0.90 KDM4E (0.48) BLMPMP22KDM4EALOX15TSHR
SCHEMBL30960193 0.89 KDM4E (0.47) BLMPMP22KDM4EALOX15TSHR
SCHEMBL15865623 0.89 KDM4E (0.47) BLMPMP22KDM4EALOX15TSHR
SCHEMBL31679405 0.88 MRGPRX4 (0.40) BLMPMP22HSD17B10KDM4EALOX15
SCHEMBL12453251 0.87 KDM4E (0.46) KDM4EALOX15TSHRACMSDTDP1
SCHEMBL23568184 0.86 KDM4E (0.50) KDM4EALOX15TSHRACMSDTDP1
SCHEMBL24627236 0.85 MRGPRX4 (0.41) BLMPMP22HSD17B10KDM4EALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12344675-B2 Polypeptide comprising a single-domain antibody variable region that binds delta-like ligand 3 (DLL3) and method of use thereof to make a radionuclide complex Abdera Therapeutics Inc. (US) 2025-07-01 US claimed
US-20250051476-A1 DLL3 BINDING MOLECULES AND USES THEREOF Abdera Therapeutics Inc. 2025-02-13 US claimed
US-20260077071-A1 Targeted Delivery of Theranostic Agents PETER MACCALLUM CANCER INST (AU) 2026-03-19 US disclosed
EP-4610269-A1 UROKINASE PLASMINOGEN ACTIVATOR SURFACE RECEPTOR (UPAR) LIGANDS FOR DIAGNOSTIC OR THERAPEUTIC USE 3B Pharmaceuticals GmbH (DE) 2025-09-03 EP disclosed
EP-4577526-A1 VHH ANTIBODY CONJUGATES Abdera Therapeutics Inc. (US) 2025-07-02 EP disclosed
EP-4577578-A1 DLL3 BINDING MOLECULES AND USES THEREOF Abdera Therapeutics Inc. (US) 2025-07-02 EP disclosed
US-12344675-B2 Polypeptide comprising a single-domain antibody variable region that binds delta-like ligand 3 (DLL3) and method of use thereof to make a radionuclide complex Abdera Therapeutics Inc. (US) 2025-07-01 US disclosed
US-20250051476-A1 DLL3 BINDING MOLECULES AND USES THEREOF Abdera Therapeutics Inc. 2025-02-13 US disclosed
EP-4493578-A1 TARGETED DELIVERY OF THERANOSTIC AGENTS Peter MacCallum Cancer Institute (AU) 2025-01-22 EP disclosed
US-20240207462-A1 IMMUNOCONJUGATES FOR TARGETED RADIOISOTOPE THERAPY Abdera Therapeutics Inc. (CA) 2024-06-27 US disclosed
WO-2024044552-A1 VHH ANTIBODY DOTA CONJUGATES Abdera Therapeutics Inc. (US) 2024-02-29 WO disclosed
WO-2024044551-A1 MULTIVALENT IMMUNOCONJUGATES FOR TARGETED RADIOISOTOPE THERAPY Abdera Therapeutics Inc. (US) 2024-02-29 WO disclosed
WO-2024044549-A1 VHH ANTIBODY CONJUGATES Abdera Therapeutics Inc. (US) 2024-02-29 WO disclosed
WO-2024044550-A1 DLL3 BINDING MOLECULES AND USES THEREOF Abdera Therapeutics Inc. (US) 2024-02-29 WO disclosed
EP-4294845-A1 IMMUNOCONJUGATES FOR TARGETED RADIOISOTOPE THERAPY Abdera Therapeutics Inc. (US) 2023-12-27 EP disclosed
WO-2023173174-A1 TARGETED DELIVERY OF THERANOSTIC AGENTS PETER MACCALLUM CANCER INSTITUTE (AU) 2023-09-21 WO disclosed
WO-2022175750-A1 IMMUNOCONJUGATES FOR TARGETED RADIOISOTOPE THERAPY Abdera Therapeutics Inc. (CA) 2022-08-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250051476-A1 DLL3 BINDING MOLECULES AND USES THEREOF DLK1, DBNL, DVL3 BLM 4451/4885PMP22 3449/4885HSD17B10 2790/4885
US-12344675-B2 Polypeptide comprising a single-domain antibody variable region that binds delta-like ligand 3 (DLL3) and method of use thereof to make a radionuclide complex DLK1, CD2BP2, IGLV6-57 BLM 4169/4885PMP22 3399/4885HSD17B10 3405/4885
US-20260077071-A1 Targeted Delivery of Theranostic Agents CCKAR, NPY1R, NPY2R BLM 1316/4885PMP22 3204/4885HSD17B10 2752/4885
US-20240207462-A1 IMMUNOCONJUGATES FOR TARGETED RADIOISOTOPE THERAPY FCGR2A, FCGR3B, CD74 BLM 3862/4885PMP22 3408/4885HSD17B10 4084/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.