Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MAP3K5 | Q99683 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25897362 | 0.85 | IDO1 (0.40) | BRD4CREBBP | |
| SCHEMBL25315720 | 0.77 | ATM (0.36) | BRD4CREBBPMAP3K5KDM4EGAA | |
| SCHEMBL25897342 | 0.76 | HIF1A (0.35) | BRD4CREBBPHIF1A | |
| SCHEMBL26967792 | 0.75 | MEN1 (0.41) | KDM4EALDH1A1GAAPOLBMAPT | |
| SCHEMBL26967782 | 0.67 | HIF1A (0.34) | BRD4HIF1AKDM4EALDH1A1GAA | |
| SCHEMBL25897361 | 0.63 | BRD9 (0.38) | BRD4CREBBPPOLBKDR | |
| SCHEMBL21241215 | 0.61 | MAPK1 (0.49) | BRD4KDM4EALDH1A1GAAPOLB | |
| SCHEMBL4662634 | 0.60 | TRPA1 (0.55) | BRD4CREBBPALDH1A1MAPT | |
| SCHEMBL4461578 | 0.60 | HPGD (0.71) | KDM4EALDH1A1GAAPOLBMAPT | |
| SCHEMBL9632140 | 0.60 | HTT (0.37) | BRD4ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4294807-A1 | TYK2 INHIBITORS AND USES THEREOF | Sudo Biosciences Limited (GB) | 2023-12-27 | — | — | EP | disclosed |