Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25897321 | 0.85 | MEN1 (0.39) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL24156660 | 0.79 | TP53 (0.38) | MEN1KMT2AMAPTCYP1A2CYP2C9 | |
| SCHEMBL26967782 | 0.77 | HIF1A (0.34) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL25316087 | 0.76 | DRD4 (0.39) | MAPTALDH1A1TP53POLB | |
| SCHEMBL25897315 | 0.76 | ADRA2A (0.36) | MEN1KMT2AMAPTCYP1A2CYP2C9 | |
| SCHEMBL25897326 | 0.76 | HIF1A (0.36) | MEN1KMT2AMAPTCYP1A2CYP2C9 | |
| SCHEMBL29766649 | 0.76 | ADRA2A (0.36) | MEN1KMT2AMAPTCYP1A2CYP2C9 | |
| SCHEMBL30703091 | 0.76 | TYK2 (0.39) | — | |
| SCHEMBL26967784 | 0.75 | BRD4 (0.33) | MAPTALDH1A1KDM4EGAAPOLB | |
| SCHEMBL25897804 | 0.73 | TYK2 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4294807-A1 | TYK2 INHIBITORS AND USES THEREOF | Sudo Biosciences Limited (GB) | 2023-12-27 | — | — | EP | disclosed |