Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 4/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | TACR1 | P25103 | 8/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | GHSR | Q92847 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26969778 | 0.91 | NPY5R (0.49) | NPY5RHDAC1HDAC6TACR1ALDH1A1 | |
| SCHEMBL26969732 | 0.87 | NPY5R (0.47) | NPY5RHDAC1HDAC6TACR1PRSS1 | |
| SCHEMBL25236263 | 0.86 | HDAC1 (0.53) | NPY5RHDAC1HDAC6TACR1GHSR | |
| SCHEMBL25274911 | 0.84 | NPY5R (0.43) | NPY5RTACR1ALDH1A1 | |
| SCHEMBL25281390 | 0.84 | TACR1 (0.48) | NPY5RHDAC1HDAC6TACR1GHSR | |
| SCHEMBL26969704 | 0.83 | NPY5R (0.43) | NPY5RTACR1 | |
| SCHEMBL30733425 | 0.82 | CYP3A4 (0.43) | NPY5RTACR1ALDH1A1 | |
| SCHEMBL26969730 | 0.81 | KCNH2 (0.46) | NPY5RTACR1 | |
| SCHEMBL26969711 | 0.81 | NPY5R (0.42) | NPY5RTACR1PRSS1PRSS2PRSS3 | |
| SCHEMBL26969738 | 0.81 | NPY5R (0.42) | NPY5RTACR1PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230416262-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. | 2023-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230416262-A1 | TRPML MODULATORS | TRPM2, TRPM4, TRPM5 | NPY5R 681/4885HDAC1 2067/4885HDAC6 526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.