Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26969737 | 0.86 | NPY5R (0.42) | ALDH1A1MEN1KMT2ANPY5RACLY | |
| SCHEMBL30733398 | 0.83 | ACLY (0.43) | MEN1KMT2ANPY5RACLYCYP3A4 | |
| SCHEMBL25274228 | 0.82 | NPY5R (0.46) | ALDH1A1SMN1; SMN2LMNANPY5RACLY | |
| SCHEMBL30733427 | 0.82 | ACLY (0.42) | TSHRMEN1KMT2ANPY5RACLY | |
| SCHEMBL25237936 | 0.81 | ACLY (0.41) | MEN1KMT2ANPY5RACLYCYP3A4 | |
| SCHEMBL26969776 | 0.81 | ACLY (0.41) | MEN1KMT2ANPY5RACLYCYP3A4 | |
| SCHEMBL26969781 | 0.81 | EPHX1 (0.44) | MEN1KMT2AMAPTNPY5RCYP3A4 | |
| SCHEMBL30733425 | 0.80 | CYP3A4 (0.43) | ALDH1A1SMN1; SMN2TSHRNPY5RACLY | |
| SCHEMBL25237931 | 0.80 | ACLY (0.41) | ALDH1A1MEN1KMT2AMAPTNPY5R | |
| SCHEMBL25239332 | 0.79 | NPY5R (0.47) | NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230416262-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. | 2023-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230416262-A1 | TRPML MODULATORS | TRPM2, TRPM4, TRPM5 | ALDH1A1 3737/4885SMN1; SMN2 1776/4885HTT 1696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.