SCHEMBL2697178

SCHEMBL2697178

CCC(CC)c1ccccc1[O]

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.41
GPR84 Q9NQS5 1/20 0.35
LMNA P02545 1/20 0.34
CCR5 P51681 1/20 0.34
POLB P06746 2/20 0.32
HTT P42858 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
PSIP1 O75475 1/20 0.31
TP53 P04637 1/20 0.31
NOS3 P29474 1/20 0.31
NOS1 P29475 1/20 0.31
NOS2 P35228 1/20 0.31
PTPRC P08575 1/20 0.31
CDC25B P30305 1/20 0.31
CYSLTR2 Q9NS75 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2697185 0.87 TSHR (0.36) TSHRGPR84LMNACCR5POLB
SCHEMBL2186068 0.85 GPR84 (0.44) TSHRGPR84LMNAPOLBPSIP1
SCHEMBL9734906 0.84 TSHR (0.48) TSHRGPR84LMNACCR5GABRA1
SCHEMBL5170875 0.83 TSHR (0.34) TSHRGPR84
SCHEMBL9632149 0.80 NR1I2 (0.46) NPSR1CYSLTR2CYSLTR1
SCHEMBL9797000 0.80 NR1I2 (0.46) NPSR1CYSLTR2CYSLTR1
SCHEMBL9276125 0.78 GABRA1 (0.41) TSHRLMNAHTTNPSR1L3MBTL1
SCHEMBL395853 0.78 TSHR (0.61) TSHRHTTL3MBTL1HDAC8GABRA1
SCHEMBL8371971 0.76 TSHR (0.39) TSHRLMNAPOLBNOS3NOS1
SCHEMBL8372941 0.76 TSHR (0.39) TSHRLMNAPOLBNPSR1NOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111655758-B Nucleic acid delivery polymers 国立大学法人东京大学 2024-03-22 CN disclosed
CN-111655758-A Polymers for nucleic acid delivery 国立大学法人东京大学 2020-09-11 CN disclosed
WO-2019151478-A1 POLYMER COMPOUND FOR NUCLEIC ACID DELIVERY 国立大学法人東京大学 2019-08-08 WO disclosed
EP-2226328-B1 PROCESS FOR PRODUCTION OF ALKYL TIN ALKOXIDE COMPOUND, AND PROCESS FOR PRODUCTION OF CARBONATE ESTER USING THE COMPOUND ASAHI KASEI CHEMICALS CORP (JP) 2012-12-26 EP disclosed
US-8168812-B2 Process for producing alkyl tin alkoxide compound and process for producing carbonic acid ester using said compound ASAHI KASEI CHEMICALS CORPORATION (JP) 2012-05-01 US disclosed
US-20100292496-A1 Process for Production of Alkyl Tin Alkoxide Compound, and Process for Production of Carbonic Acid Ester Using the Compound ASAHI KASEI KABUSHIKI KAISHA (JP) 2010-11-18 US disclosed
EP-2226328-A1 PROCESS FOR PRODUCTION OF ALKYL TIN ALKOXIDE COMPOUND, AND PROCESS FOR PRODUCTION OF CARBONATE ESTER USING THE COMPOUND Asahi Kasei Chemicals Corporation (JP) 2010-09-08 EP disclosed
US-7579485-B2 Process for producing lactone MITSUBISHI RAYON CO., LTD. (JP) 2009-08-25 US disclosed
EP-1473291-B1 PROCESS FOR PRODUCING LACTONE MITSUBISHI RAYON CO (JP) 2008-08-13 EP disclosed
US-20050080276-A1 Process for producing lactone MITSUBISHI CHEMICAL CORPORATION (JP) 2005-04-14 US disclosed
EP-1473291-A1 PROCESS FOR PRODUCING LACTONE Mitsubishi Rayon Co., Ltd. (JP) 2004-11-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050080276-A1 Process for producing lactone DCXR, MRPL21, LSS TSHR 509/4885GPR84 2376/4885LMNA 942/4885
US-20100292496-A1 Process for Production of Alkyl Tin Alkoxide Compound, and Process for Production of Carbonic Acid Ester Using the Compound OXSR1, AOC2, OXER1 TSHR 249/4885GPR84 1093/4885LMNA 3334/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.