Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 6/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.50 |
| ▸ | SRC | P12931 | 5/20 | 0.45 |
| ▸ | HCK | P08631 | 3/20 | 0.45 |
| ▸ | LCK | P06239 | 2/20 | 0.45 |
| ▸ | FYN | P06241 | 2/20 | 0.45 |
| ▸ | LYN | P07948 | 2/20 | 0.45 |
| ▸ | BLK | P51451 | 2/20 | 0.45 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.45 |
| ▸ | FRK | P42685 | 1/20 | 0.45 |
| ▸ | FGFR2 | P21802 | 5/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.45 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 2/20 | 0.43 |
| ▸ | RET | P07949 | 2/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11975 | 0.75 | PIK3CB (0.39) | KDRPDGFRBSRCHCKABL1 | |
| SCHEMBL129599 | 0.69 | PIK3CB (0.59) | KDRSRCHCKABL1PIK3CD | |
| SCHEMBL28927604 | 0.69 | BTK (0.64) | SRCHCKLCKFYNLYN | |
| SCHEMBL27088042 | 0.69 | KDR (0.54) | KDRPDGFRBHDAC1SRCHCK | |
| SCHEMBL30172740 | 0.69 | BTK (0.64) | SRCHCKLCKFYNLYN | |
| SCHEMBL20793915 | 0.68 | TTK (0.47) | KDRLCKFYNLYNBLK | |
| SCHEMBL17853710 | 0.68 | HDAC1 (0.88) | KDRPDGFRBHDAC1SRCHCK | |
| SCHEMBL20093439 | 0.68 | PIK3CD (0.46) | KDRSRCHCKFGFR4ABL1 | |
| SCHEMBL14471392 | 0.67 | SRC (0.51) | KDRPDGFRBHDAC1SRCFYN | |
| SCHEMBL20793723 | 0.67 | FAAH (0.40) | KDRSRCHCKLCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11858907-B2 | Kinase modulators | RHIZEN PHARMACEUTICALS AG (CH) | 2024-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11858907-B2 | Kinase modulators | RPS6KA1, RPS6KA2, PRKAR2A | KDR 823/4885PDGFRB 623/4885HDAC1 1708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.