Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 5/20 | 0.67 |
| ▸ | SIRT1 | Q96EB6 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.46 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26974401 | 0.92 | PIK3CG (0.79) | PIK3CGSIRT1MAPTNPC1KDM4E | |
| SCHEMBL26974370 | 0.84 | PIK3CG (0.66) | PIK3CGMAPTNPC1KDM4ELMNA | |
| SCHEMBL684876 | 0.83 | PIK3CG (0.84) | PIK3CGSIRT1MAPTNPC1KDM4E | |
| SCHEMBL26974376 | 0.82 | SIRT1 (0.83) | PIK3CGSIRT1MAPTNPC1KDM4E | |
| SCHEMBL26974400 | 0.81 | PIK3CG (0.80) | PIK3CGMAPTNPC1KDM4ELMNA | |
| SCHEMBL26974365 | 0.81 | PIK3CG (0.60) | PIK3CGSIRT1MAPTNPC1KDM4E | |
| SCHEMBL684745 | 0.80 | PIK3CG (0.83) | PIK3CGSIRT1MAPTNPC1KDM4E | |
| SCHEMBL26974385 | 0.80 | PIK3CG (0.58) | PIK3CGSIRT1MAPTNPC1KDM4E | |
| SCHEMBL684801 | 0.78 | PIK3CG (0.79) | PIK3CGSIRT1MAPTNPC1KDM4E | |
| SCHEMBL26974380 | 0.77 | SIRT1 (0.67) | PIK3CGSIRT1MAPTNPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11858880-B2 | Anti-fungals compounds targeting the synthesis of fungal sphingolipids | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2024-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11858880-B2 | Anti-fungals compounds targeting the synthesis of fungal sphingolipids | ERG28, UGCG, DPM1 | PIK3CG 488/4885SIRT1 2412/4885MAPT 2146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.