Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 8/20 | 0.54 |
| ▸ | SORT1 | Q99523 | 8/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | GALR3 | O60755 | 2/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | LTK | P29376 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26976513 | 0.86 | GRN (0.58) | GRNSORT1KDM4ENPC1MAPK13 | |
| SCHEMBL26976574 | 0.81 | GRN (0.38) | GRNSORT1KDM4EMEN1KMT2A | |
| SCHEMBL30559528 | 0.73 | CDK8 (0.47) | GRNSORT1KDM4ENPC1MAPK13 | |
| SCHEMBL22637140 | 0.71 | KLKB1 (0.44) | GRNSORT1KDM4EMAPK13MAPK12 | |
| SCHEMBL1572486 | 0.71 | GRN (1.00) | GRNSORT1KDM4ENPC1MAPK13 | |
| SCHEMBL3761678 | 0.71 | GRN (0.58) | GRNSORT1KDM4ENPC1MAPK14 | |
| Hydrochloric Acid SCHEMBL8760885 | 0.69 | GRN (0.96) | GRNSORT1KDM4ENPC1MAPK13 | |
| SCHEMBL3186489 | 0.69 | GRN (0.56) | GRNSORT1KDM4ENPC1MAPK14 | |
| SCHEMBL26976579 | 0.68 | KMT2A (0.40) | GRNSORT1KDM4EMAPK13MAPK12 | |
| SCHEMBL950587 | 0.68 | NR3C2 (0.46) | GRNSORT1KDM4EMAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4619388-A1 | CATHEPSIN L INHIBITORS | Biofront Therapeutics (Beijing) Co., Ltd. (CN) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024140356-A1 | CATHEPSIN L INHIBITORS | BIOFRONT THERAPEUTICS (BEIJING) CO., LTD. (CN) | 2024-07-04 | — | — | WO | disclosed |
| US-11858905-B1 | Cathepsin L inhibitors | BIOFRONT THERAPEUTICS (BEIJING) CO., LTD. (CN) | 2024-01-02 | — | — | US | disclosed |
| CN-116589425-A | Cathepsin L inhibitors | 百放英库医药科技(北京)有限公司 | 2023-08-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11858905-B1 | Cathepsin L inhibitors | CTSV, CTSL, CTSB | GRN 816/4885SORT1 616/4885KDM4E 4319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.