SCHEMBL2697742

SCHEMBL2697742

CC(=O)N1CC=NC=C1c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.38
ALDH1A1 P00352 2/20 0.38
HSD17B3 P37058 2/20 0.37
CYP11B1 P15538 1/20 0.36
CYP11B2 P19099 1/20 0.36
NR1H2 P55055 1/20 0.36
NR1H3 Q13133 1/20 0.36
CYP1A2 P05177 1/20 0.36
MAOB P27338 1/20 0.36
NOTUM Q6P988 5/20 0.36
MAPT P10636 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
BRD4 O60885 1/20 0.34
SMO Q99835 1/20 0.34
RPA1 P27694 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1974655 0.76 SMN1; SMN2 (0.35) KDM4EALDH1A1NR1H2NR1H3SMN1; SMN2
SCHEMBL7944913 0.63 POLB (0.57) KDM4EALDH1A1CYP11B1CYP11B2NOTUM
SCHEMBL2511500 0.61
Biphenyl SCHEMBL1822628 0.60 SMN1; SMN2 (0.67) KDM4EALDH1A1MAPTSMN1; SMN2
Biphenyl SCHEMBL538359 0.60 SMN1; SMN2 (0.67) KDM4EALDH1A1MAPTSMN1; SMN2
Biphenyl SCHEMBL15332958 0.60 SMN1; SMN2 (0.67) KDM4EALDH1A1MAPTSMN1; SMN2
Biphenyl SCHEMBL29059196 0.60 SMN1; SMN2 (0.67) KDM4EALDH1A1MAPTSMN1; SMN2
SCHEMBL1966470 0.59 SMN1; SMN2 (0.46) ALDH1A1NR1H2NR1H3CYP1A2NOTUM
SCHEMBL8539984 0.59
Biphenyl SCHEMBL9789299 0.58 SMN1; SMN2 (0.64) KDM4EALDH1A1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8845850-B2 Anaerobic adhesive and sealant compositions in film form, film spool assemblies containing such compositions in film form and preapplied versions thereof on matable parts Henkel US IP LLC (US) 2014-09-30 US disclosed
US-20130071202-A1 ANAEROBIC ADHESIVE AND SEALANT COMPOSITIONS IN FILM FORM, FILM SPOOL ASSEMBLIES CONTAINING SUCH COMPOSITIONS IN FILM FORM AND PREAPPLIED VERSIONS THEREOF ON MATABLE PARTS HENKEL CORPORATION (US) 2013-03-21 US disclosed
US-8333866-B2 Anaerobic adhesive and sealant compositions in film form, film spool assemblies containing such compositions in film form and preapplied versions thereof on matable parts HENKEL CORPORATION (US) 2012-12-18 US disclosed
US-20120114898-A1 ANAEROBIC ADHESIVE AND SEALANT COMPOSITIONS IN FILM FORM, FILM SPOOL ASSEMBLIES CONTAINING SUCH COMPOSITIONS IN FILM FORM AND PREAPPLIED VERSIONS THEREOF ON MATABLE PARTS HENKEL CORPORATION (US) 2012-05-10 US disclosed