Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936614 | 0.86 | MEN1 (0.58) | POLBMEN1KMT2ATHRBALDH1A1 | |
| SCHEMBL11713523 | 0.76 | HDAC3 (0.60) | POLBMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL11711884 | 0.70 | OPRK1 (0.69) | ALDH1A1NOTUMMAPTSMN1; SMN2GAA | |
| SCHEMBL7547109 | 0.70 | ALDH1A1 (0.51) | POLBKMT2AALDH1A1KDM4ENOTUM | |
| SCHEMBL9636319 | 0.69 | GAA (0.44) | POLBMEN1KMT2ATHRBALDH1A1 | |
| Propane SCHEMBL29156530 | 0.69 | NPC1 (0.59) | POLBMEN1KMT2ATHRBALDH1A1 | |
| SCHEMBL28172958 | 0.68 | CA1 (0.49) | MEN1KMT2AALDH1A1GAARECQL | |
| SCHEMBL5121302 | 0.68 | CA1 (0.66) | — | |
| SCHEMBL124028 | 0.68 | POLB (0.46) | POLBMEN1KMT2ATHRBALDH1A1 | |
| SCHEMBL14225764 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258915-B1 | URETIDONE-FUNCTONAL POLYISOCYANATE | DEGUSSA-HUELS AKTIENGESELLSCHAFT (DE) | 2001-07-10 | — | — | US | disclosed |
| EP-0999226-A1 | Solid polyurethane curing agents showing triazine groups, process for their preparation and their use | Degussa-Hüls Aktiengesellschaft (DE) | 2000-05-10 | — | — | EP | disclosed |