Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.35 |
| ▸ | EBP | Q15125 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2701172 | 1.00 | TSHR (0.42) | TSHRTHRBALDH1A1EPHX1HTT | |
| SCHEMBL11598846 | 0.97 | TSHR (0.40) | TSHRTHRBALDH1A1EPHX1HTT | |
| SCHEMBL19292785 | 0.95 | ALDH1A1 (0.36) | TSHRTHRBALDH1A1EPHX1HTT | |
| SCHEMBL6750459 | 0.89 | TSHR (0.47) | TSHRTHRBALDH1A1EPHX1HTT | |
| SCHEMBL6524652 | 0.89 | TSHR (0.47) | TSHRTHRBALDH1A1EPHX1HTT | |
| SCHEMBL4367088 | 0.89 | TSHR (0.47) | TSHRTHRBALDH1A1EPHX1HTT | |
| SCHEMBL525644 | 0.89 | — | — | |
| SCHEMBL20972491 | 0.86 | CYP1A2 (0.33) | TSHRTHRBLMNA | |
| SCHEMBL4362974 | 0.86 | TSHR (0.41) | TSHRTHRBALDH1A1EPHX1HTT | |
| SCHEMBL5547934 | 0.83 | MEN1 (0.41) | TSHRTHRBALDH1A1HTTGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105348297-A | Cage-shaped cyclopentanoic dianhydride, method for production thereof, and polyimide | NISSAN CHEMICAL IND LTD | 2016-02-24 | — | — | CN | disclosed |
| US-8975365-B2 | Cage-shaped cyclopentanoic dianhydride, method for production thereof, and polyimide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2015-03-10 | — | — | US | disclosed |
| US-20140114027-A1 | CAGE-SHAPED CYCLOPENTANOIC DIANHYDRIDE, METHOD FOR PRODUCTION THEREOF, AND POLYIMIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2014-04-24 | — | — | US | disclosed |
| US-8658743-B2 | Cage-shaped cyclopentanoic dianhydride, method for production thereof, and polyimide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2014-02-25 | — | — | US | disclosed |
| US-20120108759-A1 | CAGE-SHAPED CYCLOPENTANOIC DIANHYDRIDE, METHOD FOR PRODUCTION THEREOF, AND POLYIMIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-05-03 | — | — | US | disclosed |
| US-20100292421-A1 | BRIDGED METALLOCENE COMPOUND, OLEFIN POLYMERIZATION CATALYST CONTAINING THE SAME, AND ETHYLENE POLYMER OBTAINED WITH THE CATALYST | MITSUI CHEMICALS, INC. | 2010-11-18 | — | — | US | disclosed |
| EP-2218725-A1 | BRIDGED METALLOCENE COMPOUND, OLEFIN POLYMERIZATION CATALYST USING THE COMPOUND AND ETHYLENE POLYMER OBTAINED BY USING THE CATALYST | Mitsui Chemicals, Inc. (JP) | 2010-08-18 | — | — | EP | disclosed |
| EP-0963382-B2 | POLYMERIZATION CATALYST SYSTEMS COMPRISING HETEROCYCLIC FUSED CYCLOPENTADIENIDE LIGANDS | EXXONMOBIL CHEM PATENTS INC (US) | 2008-07-02 | — | — | EP | disclosed |
| US-6451938-B1 | CATALYTIC COMPLEX FORMED BY ACTIVATING TRANSITION METAL COMPOUNDS COMPRISING CYCLOPENTADIENIDE ANIONS WHICH BEAR FUSED HETEROCYCLIC RINGS | EXXON MOBIL CHEMICAL PATENTS INC. | 2002-09-17 | — | — | US | disclosed |
| EP-0963382-B1 | POLYMERIZATION CATALYST SYSTEMS COMPRISING HETEROCYCLIC FUSED CYCLOPENTADIENIDE LIGANDS | EXXONMOBIL CHEM PATENTS INC (US) | 2001-11-14 | — | — | EP | disclosed |
| EP-0963382-A1 | POLYMERIZATION CATALYST SYSTEMS COMPRISING HETEROCYCLIC FUSED CYCLOPENTADIENIDE LIGANDS | EXXON CHEMICAL PATENTS INC. (US) | 1999-12-15 | — | — | EP | disclosed |
| WO-1998037106-A1 | POLYMERIZATION CATALYST SYSTEMS COMPRISING HETEROCYCLIC FUSED CYCLOPENTADIENIDE LIGANDS | EXXON CHEMICAL PATENTS INC. (US) | 1998-08-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108759-A1 | CAGE-SHAPED CYCLOPENTANOIC DIANHYDRIDE, METHOD FOR PRODUCTION THEREOF, AND POLYIMIDE | DCUN1D4, DCUN1D1, AMD1 | TSHR 3630/4885THRB 4798/4885ALDH1A1 353/4885 |
| US-20140114027-A1 | CAGE-SHAPED CYCLOPENTANOIC DIANHYDRIDE, METHOD FOR PRODUCTION THEREOF, AND POLYIMIDE | DCUN1D4, DCUN1D1, AMD1 | TSHR 3630/4885THRB 4798/4885ALDH1A1 353/4885 |
| US-20100292421-A1 | BRIDGED METALLOCENE COMPOUND, OLEFIN POLYMERIZATION CATALYST CONTAINING THE SAME, AND ETHYLENE POLYMER OBTAINED WITH THE CATALYST | CAD, ENDOD1, CCT7 | TSHR 4068/4885THRB 2758/4885ALDH1A1 979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.