Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.51 |
| ▸ | KDM4A | O75164 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16961721 | 0.82 | CYP1A2 (0.59) | ALDH1A1SMN1; SMN2MAPTGAARAB9A | |
| SCHEMBL31330663 | 0.80 | KDM4C (0.51) | ALDH1A1KDM4ESMN1; SMN2TDP1KDM4C | |
| SCHEMBL9943788 | 0.79 | JAK2 (0.55) | ALDH1A1KDM4ESMN1; SMN2TDP1MAPT | |
| SCHEMBL3017686 | 0.78 | CYP1A2 (0.58) | ALDH1A1KDM4ETDP1MAPTGAA | |
| SCHEMBL256096 | 0.75 | MAPT (0.56) | ALDH1A1KDM4ETDP1MAPTGAA | |
| SCHEMBL28896334 | 0.75 | CYP1A2 (0.70) | ALDH1A1KDM4ESMN1; SMN2MAPTGAA | |
| SCHEMBL4717450 | 0.74 | POLB (0.50) | ALDH1A1KDM4ESMN1; SMN2MAPTGAA | |
| SCHEMBL9898080 | 0.74 | HPGD (0.69) | ALDH1A1KDM4ESMN1; SMN2MAPTNPC1 | |
| Bicarbonate SCHEMBL31330809 | 0.73 | KDM4E (0.47) | ALDH1A1KDM4ESMN1; SMN2TDP1KDM4C | |
| SCHEMBL16638510 | 0.72 | CYP1A2 (0.47) | ALDH1A1KDM4ESMN1; SMN2MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4551575-A2 | TREM2 MODULATORS | Muna Therapeutics ApS (DK) | 2025-05-14 | — | — | EP | disclosed |
| CN-119403806-A | TREM2 modulators | 穆纳治疗有限公司 | 2025-02-07 | — | — | CN | disclosed |
| WO-2024008722-A2 | TREM2 MODULATORS | MUNA THERAPEUTICS APS (DK) | 2024-01-11 | — | — | WO | disclosed |
| WO-2024008722-A2 | TREM2 MODULATORS | MUNA THERAPEUTICS APS (DK) | 2024-01-11 | — | — | WO | disclosed |