Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3017686 | 0.78 | CYP1A2 (0.58) | CYP1A2CYP2C9CYP2C19LMNAHPGD | |
| SCHEMBL256096 | 0.75 | MAPT (0.56) | CYP1A2CYP2C9CYP2C19LMNAHPGD | |
| SCHEMBL16961721 | 0.75 | CYP1A2 (0.59) | CYP1A2CYP2C9CYP2C19LMNAHPGD | |
| SCHEMBL9943788 | 0.72 | JAK2 (0.55) | CYP1A2CYP2C9CYP2C19LMNAHPGD | |
| SCHEMBL15330350 | 0.72 | ALDH1A1 (0.59) | CYP1A2CYP2C9CYP2C19LMNAHPGD | |
| SCHEMBL26988884 | 0.72 | ALDH1A1 (0.60) | CYP1A2CYP2C9CYP2C19LMNAHPGD | |
| SCHEMBL2932942 | 0.71 | CYP1A2 (0.59) | CYP1A2CYP2C9CYP2C19LMNAHPGD | |
| SCHEMBL10925750 | 0.70 | MAPT (0.51) | CYP1A2CYP2C9CYP2C19LMNAHPGD | |
| SCHEMBL11648197 | 0.69 | CYP1A2 (0.66) | CYP1A2CYP2C9CYP2C19LMNAHPGD | |
| Hydrochloric Acid SCHEMBL10926845 | 0.69 | MAPT (0.50) | CYP1A2CYP2C9CYP2C19HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150173359-A1 | SUBSTITUTED FUSED PYRIMIDINONES AND DIHYDROPYRIMIDINONES | BAYER IP GMBH (DE) | 2015-06-25 | — | — | US | disclosed |
| US-9006265-B2 | Substituted fused pyrimidinones and dihydropyrimidinones | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150173359-A1 | SUBSTITUTED FUSED PYRIMIDINONES AND DIHYDROPYRIMIDINONES | DHPS, FDPS, DPYD | CYP1A2 862/4885CYP2C9 963/4885CYP2C19 392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.