Azelaic Acid

Azelaic Acid

SCHEMBL2699067

C1CCCNCC1.N.O=C(O)CCCCCCCC(=O)O

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.55
LMNA P02545 3/20 0.55
NFKB1 P19838 1/20 0.55
PMP22 Q01453 1/20 0.55
GPR84 Q9NQS5 8/20 0.46
FFAR1 O14842 2/20 0.46
FFAR4 Q5NUL3 2/20 0.46
PPARG P37231 7/20 0.44
PPARD Q03181 7/20 0.44
PPARA Q07869 7/20 0.44
HDAC11 Q96DB2 5/20 0.44
ALDH1A1 P00352 3/20 0.44
PTPN1 P18031 3/20 0.44
TLR2 O60603 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
MEN1 O00255 2/20 0.44
FABP4 P15090 2/20 0.44
ALOX15 P16050 2/20 0.44
KMT2A Q03164 2/20 0.44
SLC22A6 Q4U2R8 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sebacic Acid SCHEMBL2287927 1.00 TSHR (0.55) TSHRLMNANFKB1PMP22GPR84
Azepane SCHEMBL18063297 1.00 TSHR (0.55) TSHRLMNANFKB1PMP22GPR84
Azepane SCHEMBL19063520 1.00 TSHR (0.55) TSHRLMNANFKB1PMP22GPR84
Sebacic Acid SCHEMBL5874996 0.98 TSHR (0.57) TSHRLMNANFKB1PMP22GPR84
Adipic Acid SCHEMBL2293630 0.98 LMNA (0.52) TSHRLMNANFKB1PMP22GPR84
Sebacic Acid SCHEMBL5875002 0.98 TSHR (0.57) TSHRLMNANFKB1PMP22GPR84
Adipic Acid SCHEMBL18091137 0.98 LMNA (0.52) TSHRLMNANFKB1PMP22GPR84
Sebacic Acid SCHEMBL11610099 0.98 TSHR (0.57) TSHRLMNANFKB1PMP22GPR84
Pyrrolidine SCHEMBL9249608 0.95 TSHR (0.60) TSHRLMNANFKB1PMP22GPR84
Adipic Acid SCHEMBL16670398 0.95 LMNA (0.55) TSHRLMNANFKB1PMP22GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105164181-B Flameproof polyamide, Its Preparation Method And Use 德国登肯多夫纺织与纤维研究学院 2018-09-04 CN claimed
CN-1671551-A Film comprising a gas barrier layer CFS KEMPTEN GMBH (DE) 2005-09-21 CN claimed
EP-0617072-B1 Barrier layers made of transparent copolyamide INVENTA AG (CH) 1997-09-03 EP claimed
JP-7003012-A None JP disclosed
CN-105164181-B Flameproof polyamide, Its Preparation Method And Use 德国登肯多夫纺织与纤维研究学院 2018-09-04 CN disclosed
US-20170260554-A1 Method For The Enzyme-Catalyzed Production Of Prepolymers For Producing Plastics Karlsruher Institut für Technologie (DE) 2017-09-14 US disclosed
US-8841373-B2 Borophosphate, borate phosphate, and metal borophosphate as novel flame proofing additives for plastics BASF SE (DE) 2014-09-23 US disclosed
US-20120108713-A1 BOROPHOSPHATE, BORATE PHOSPHATE, AND METAL BOROPHOSPHATE AS NOVEL FLAME PROOFING ADDITIVES FOR PLASTICS BASF SE (DE) 2012-05-03 US disclosed
CN-1671551-A Film comprising a gas barrier layer CFS KEMPTEN GMBH (DE) 2005-09-21 CN disclosed
JP-H073012-A TRANSPARENT COPOLYAMIDE, BARRIER MADE OF THIS COPOLYAMIDE AND MULTI-LAYERED COMPLEX HAVING THIS BARRIER EMS INVENTA AG 1995-01-06 JP disclosed
US-4483975-A Copolyetheresteramides, process for their production and their use for the heat-sealing of textiles PLATE BONN GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1984-11-20 US disclosed