Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | PPARD | Q03181 | 4/20 | 0.41 |
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL18091137 | 1.00 | LMNA (0.52) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Azelaic Acid SCHEMBL2699067 | 0.98 | TSHR (0.55) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Sebacic Acid SCHEMBL2287927 | 0.98 | TSHR (0.55) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Azepane SCHEMBL18063297 | 0.98 | TSHR (0.55) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Azepane SCHEMBL19063520 | 0.98 | TSHR (0.55) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL16670398 | 0.98 | LMNA (0.55) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL2699798 | 0.98 | LMNA (0.55) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL5874393 | 0.98 | LMNA (0.55) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL5874403 | 0.98 | LMNA (0.55) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL336949 | 0.98 | LMNA (0.55) | LMNATSHRNFKB1PMP22SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240026154-A1 | POLYAMIDE COMPOSITIONS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2024-01-25 | — | — | US | claimed |
| CN-110305469-B | Polyamide composite material for gas-assisted molding and preparation method and application thereof | 中广核俊尔(浙江)新材料有限公司 | 2021-04-09 | — | — | CN | claimed |
| EP-3328916-B1 | FLAME-RESISTANT POLYAMIDE AS REACTION PRODUCT OF A LACTAM, AND METHOD FOR THE PRODUCTION AND USE THEREOF | DEUTSCHE INST FUER TEXTIL UND FASERFORSCHUNG DENKENDORF (DE) | 2019-11-20 | — | — | EP | claimed |
| CN-105164181-B | Flameproof polyamide, Its Preparation Method And Use | 德国登肯多夫纺织与纤维研究学院 | 2018-09-04 | — | — | CN | claimed |
| CN-107856386-A | Multilayer hollow body with high leaching resistance | 赢创德固赛有限公司 | 2018-03-30 | — | — | CN | claimed |
| CN-100450772-C | Multi-layer composite comprising an evoh layer and a protective layer | DEGUSSA (DE) | 2009-01-14 | — | — | CN | claimed |
| CN-100391734-C | Multi layer composite material containing EVOH layer | DEGUSSA (DE) | 2008-06-04 | — | — | CN | claimed |
| CN-1878671-A | Multi-layer composite comprising an evoh layer and a protective layer | DEGUSSA (DE) | 2006-12-13 | — | — | CN | claimed |
| CN-1671551-A | Film comprising a gas barrier layer | CFS KEMPTEN GMBH (DE) | 2005-09-21 | — | — | CN | claimed |
| CN-1187185-C | Polyamide composite material with double or multiple layers | DEGUSSA (DE) | 2005-02-02 | — | — | CN | claimed |
| CN-1378913-A | Multi layer composite material containing EVOH layer | DEGUSSA (DE) | 2002-11-13 | — | — | CN | claimed |
| CN-1361005-A | Polyamide composite material with double or multiple layers | DEGUSSA (DE) | 2002-07-31 | — | — | CN | claimed |
| US-5756571-A | MELAMINE COMPOUND | AGRINUTRIENTS COMPANY, INC. (US) | 1998-05-26 | — | — | US | claimed |
| EP-0617072-B1 | Barrier layers made of transparent copolyamide | INVENTA AG (CH) | 1997-09-03 | — | — | EP | claimed |
| EP-0062822-B1 | LAMINATED SHEETS AND DEEP-DRAWN CONTAINERS MADE THEREFROM | Wolff Walsrode Aktiengesellschaft (DE) | 1985-05-29 | — | — | EP | claimed |
| US-4480011-A | CHORINATED NATURAL RUBBER | INSTITUT FRANCAIS DU PETROLE (FR) | 1984-10-30 | — | — | US | claimed |
| US-4361609-A | Fiber structures of split multicomponent fibers and process therefor | AKZONA INCORPORATED (US) | 1982-11-30 | — | — | US | claimed |
| EP-0010007-B1 | METHOD FOR RESTORING BASIC PAINT COATINGS | SOCIETE FRANCAISE DUCO Société anonyme (FR) | 1981-09-09 | — | — | EP | claimed |
| US-4273808-A | POLYAMIDE IN ALCOHOL SOLVENT | SOCIETE FRANCAISE DUCO (FR) | 1981-06-16 | — | — | US | claimed |
| US-4239720-A | Fiber structures of split multicomponent fibers and process therefor | AKZONA INCORPORATED (US) | 1980-12-16 | — | — | US | claimed |