Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | PPARD | Q03181 | 4/20 | 0.42 |
| ▸ | PPARA | Q07869 | 4/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL5874403 | 1.00 | LMNA (0.55) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL336949 | 1.00 | LMNA (0.55) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL5874393 | 1.00 | LMNA (0.55) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL18091137 | 0.98 | LMNA (0.52) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Sebacic Acid SCHEMBL5875002 | 0.98 | TSHR (0.57) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL2293630 | 0.98 | LMNA (0.52) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Sebacic Acid SCHEMBL11610099 | 0.98 | TSHR (0.57) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Sebacic Acid SCHEMBL5874996 | 0.98 | TSHR (0.57) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Azepane SCHEMBL18063297 | 0.95 | TSHR (0.55) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Azelaic Acid SCHEMBL2699067 | 0.95 | TSHR (0.55) | LMNATSHRNFKB1PMP22SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3060591-A1 | COPOLYMERS AND COMPOSITIONS WITH ANTI-ADHESIVE AND ANTIMICROBIAL PROPERTIES | BASF SE (DE) | 2016-08-31 | — | — | EP | disclosed |
| US-20160235062-A1 | COPOLYMERS AND COMPOSITIONS WITH ANTI-ADHESIVE AND ANTIMICROBIAL PROPERTIES | BASF SE (DE) | 2016-08-18 | — | — | US | disclosed |
| WO-2015132707-A1 | CORE-SHELL PARTICLES COMPRISING LOW BULK DENSITY CARBON IN THE SHELL | BASF SE (DE) | 2015-09-11 | — | — | WO | disclosed |
| WO-2015058964-A1 | COPOLYMERS AND COMPOSITIONS WITH ANTI-ADHESIVE AND ANTIMICROBIAL PROPERTIES | BASF SE (DE) | 2015-04-30 | — | — | WO | disclosed |
| WO-2015061097-A1 | LUBRICIOUS, ANTI-ADHESIVE COATINGS | BASF SE (DE) | 2015-04-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160235062-A1 | COPOLYMERS AND COMPOSITIONS WITH ANTI-ADHESIVE AND ANTIMICROBIAL PROPERTIES | MACF1, ITGA5, ILK | LMNA 4514/4885TSHR 4735/4885NFKB1 3062/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.