SCHEMBL2699797

SCHEMBL2699797

O=C1C=CC(=O)N1c1c(F)c(F)c(-c2c(F)c(F)c(N3C(=O)C=CC3=O)c(F)c2F)c(F)c1F

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 14/20 0.43
FAAH O00519 6/20 0.40
BCHE P06276 1/20 0.38
TLR9 Q9NR96 1/20 0.37
HSP90AA1 P07900 3/20 0.33
CCR6 P51684 2/20 0.33
PKM P14618 2/20 0.33
MAPK1 P28482 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
GSK3A P49840 1/20 0.32
GSK3B P49841 1/20 0.32
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
HPGD P15428 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7264420 0.92 MGLL (0.48) MGLLFAAHBCHETLR9HSP90AA1
SCHEMBL718457 0.90 MGLL (0.46) MGLLFAAHBCHETLR9HSP90AA1
SCHEMBL24702075 0.88 MGLL (0.35) MGLLFAAHBCHETLR9HSP90AA1
SCHEMBL24702073 0.87 MGLL (0.44) MGLLFAAHBCHETLR9HSP90AA1
SCHEMBL16768814 0.81 MGLL (0.40) MGLLFAAHBCHETLR9HSP90AA1
SCHEMBL6834882 0.81 MGLL (0.40) MGLLFAAHBCHETLR9HSP90AA1
SCHEMBL24702076 0.79 MGLL (0.39) MGLLFAAHBCHETLR9HSP90AA1
SCHEMBL24702072 0.79 MGLL (0.39) MGLLFAAHBCHETLR9HSP90AA1
SCHEMBL6833150 0.76 MGLL (0.41) MGLLFAAHBCHETLR9HSP90AA1
SCHEMBL10183500 0.74 MGLL (0.35) MGLLFAAHBCHETLR9HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220396683-A1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND CROSS-LINKED PRODUCT THEREOF, AND COMPOUND AGC Inc. (JP) 2022-12-15 US disclosed
US-20220389132-A1 FLUORINE-CONTAINING POLYMER AND METHOD OF PRODUCING SAME AGC Inc. (JP) 2022-12-08 US disclosed
US-9194981-B2 Mercaptofunctional high mubeta EO chromophores and high TG, low optical loss, covalently bonded, high mubeta EO chromophore containing polymers and methods of synthesizing EO materials CORNING INCORPORATED (US) 2015-11-24 US disclosed
US-9194981-B2 Mercaptofunctional high mubeta EO chromophores and high TG, low optical loss, covalently bonded, high mubeta EO chromophore containing polymers and methods of synthesizing EO materials CORNING INCORPORATED (US) 2015-11-24 US disclosed
US-9194981-B2 Mercaptofunctional high mubeta EO chromophores and high TG, low optical loss, covalently bonded, high mubeta EO chromophore containing polymers and methods of synthesizing EO materials CORNING INCORPORATED (US) 2015-11-24 US disclosed
EP-2450355-B1 Mercaptofunctional high uB EO chromophores and high tg, low optical loss, covalently bonded, high uB EO chromophore containing polymers and methods of synthesizing EO materials CORNING INC (US) 2014-09-10 EP disclosed
EP-2450355-B1 Mercaptofunctional high uB EO chromophores and high tg, low optical loss, covalently bonded, high uB EO chromophore containing polymers and methods of synthesizing EO materials CORNING INC (US) 2014-09-10 EP disclosed
US-20140246631-A1 MERCAPTOFUNCTIONAL HIGH MUBETA EO CHROMOPHORES AND HIGH TG, LOW OPTICAL LOSS, COVALENTLY BONDED, HIGH MUBETA EO CHROMOPHORE CONTAINING POLYMERS AND METHODS OF SYNTHESIZING EO MATERIALS CORNING INCORPORATED (US) 2014-09-04 US disclosed
US-20140246631-A1 MERCAPTOFUNCTIONAL HIGH MUBETA EO CHROMOPHORES AND HIGH TG, LOW OPTICAL LOSS, COVALENTLY BONDED, HIGH MUBETA EO CHROMOPHORE CONTAINING POLYMERS AND METHODS OF SYNTHESIZING EO MATERIALS CORNING INCORPORATED (US) 2014-09-04 US disclosed
US-20140246631-A1 MERCAPTOFUNCTIONAL HIGH MUBETA EO CHROMOPHORES AND HIGH TG, LOW OPTICAL LOSS, COVALENTLY BONDED, HIGH MUBETA EO CHROMOPHORE CONTAINING POLYMERS AND METHODS OF SYNTHESIZING EO MATERIALS CORNING INCORPORATED (US) 2014-09-04 US disclosed
EP-2450355-A1 Mercaptofunctional high uB EO chromophores and high tg, low optical loss, covalently bonded, high uB EO chromophore containing polymers and methods of synthesizing EO materials Corning Incorporated (US) 2012-05-09 EP disclosed
US-20100193753-A1 MERCAPTOFUNCTIONAL HIGH MUBETA EO CHROMOPHORES AND HIGH TG, LOW OPTICAL LOSS, COVALENTLY BONDED, HIGH MUBETA EO CHROMOPHORE CONTAINING POLYMERS AND METHODS OF SYNTHESIZING EO MATERIALS HE MINGQIAN 2010-08-05 US disclosed
US-20100193753-A1 MERCAPTOFUNCTIONAL HIGH MUBETA EO CHROMOPHORES AND HIGH TG, LOW OPTICAL LOSS, COVALENTLY BONDED, HIGH MUBETA EO CHROMOPHORE CONTAINING POLYMERS AND METHODS OF SYNTHESIZING EO MATERIALS HE MINGQIAN 2010-08-05 US disclosed
US-20100193753-A1 MERCAPTOFUNCTIONAL HIGH MUBETA EO CHROMOPHORES AND HIGH TG, LOW OPTICAL LOSS, COVALENTLY BONDED, HIGH MUBETA EO CHROMOPHORE CONTAINING POLYMERS AND METHODS OF SYNTHESIZING EO MATERIALS HE MINGQIAN 2010-08-05 US disclosed
US-7723462-B2 electrooptic (EO) devices; chromophores bond to polyimidosulfide polymers producing high glass transition temperature, low optical loss CORNING INCORPORATED (US) 2010-05-25 US disclosed
US-7723462-B2 electrooptic (EO) devices; chromophores bond to polyimidosulfide polymers producing high glass transition temperature, low optical loss CORNING INCORPORATED (US) 2010-05-25 US disclosed
US-7723462-B2 electrooptic (EO) devices; chromophores bond to polyimidosulfide polymers producing high glass transition temperature, low optical loss CORNING INCORPORATED (US) 2010-05-25 US disclosed
US-20070257237-A1 electrooptic (EO) devices; chromophores bond to polyimidosulfide polymers producing high glass transition temperature, low optical loss CORNING INCORPORATED 2007-11-08 US disclosed
US-20070257237-A1 electrooptic (EO) devices; chromophores bond to polyimidosulfide polymers producing high glass transition temperature, low optical loss CORNING INCORPORATED 2007-11-08 US disclosed
US-20070257237-A1 electrooptic (EO) devices; chromophores bond to polyimidosulfide polymers producing high glass transition temperature, low optical loss CORNING INCORPORATED 2007-11-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220396683-A1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND CROSS-LINKED PRODUCT THEREOF, AND COMPOUND FEM1B, AFF4, FLI1 MGLL 2072/4885FAAH 2068/4885BCHE 2361/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.