SCHEMBL26999067

SCHEMBL26999067

O=c1ccc(-c2cnc(OCC3CCC3)nc2)nn1Cc1cccc(F)c1

nearest known ligand 0.49

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ MET P08581 15/20 0.49
▸ NQO2 P16083 1/20 0.48
▸ HTT P42858 1/20 0.43
▸ NPSR1 Q6W5P4 1/20 0.43
▸ MEN1 O00255 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ CHEK1 O14757 1/20 0.42
▸ NEK2 P51955 1/20 0.42
▸ LIMK1 P53667 1/20 0.42
▸ TYRO3 Q06418 1/20 0.42
▸ CLK4 Q9HAZ1 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26999056 0.96 MET (0.50) METNQO2MEN1KMT2ACHEK1
SCHEMBL23528315 0.89 MET (0.40) METNQO2MEN1KMT2A
SCHEMBL26999046 0.89 MET (0.48) METNQO2MEN1KMT2ACHEK1
SCHEMBL23528527 0.85 MET (0.41) METNQO2MEN1KMT2A
SCHEMBL26999027 0.83 MET (0.56) METMEN1KMT2ACHEK1NEK2
SCHEMBL26999075 0.83 MET (0.53) METHTTNPSR1MEN1KMT2A
SCHEMBL26999029 0.82 MET (0.57) METMEN1KMT2ACHEK1NEK2
SCHEMBL29776791 0.82 MET (0.52) METMEN1KMT2ACHEK1NEK2
SCHEMBL23297321 0.82 MET (0.52) METMEN1KMT2ACHEK1NEK2
SCHEMBL26999052 0.82 MET (0.52) METMEN1KMT2ACHEK1NEK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11873290-B2 — — 2024-01-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11873290-B2 — IL6, MUSK, IL6ST MET 4344/4885NQO2 1023/4885HTT 2657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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