Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 9/20 | 0.43 |
| ▸ | ATRIP | Q8WXE1 | 8/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 7/20 | 0.35 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26999180 | 0.87 | ATR (0.38) | ATRATRIPROCK2PIK3R2PIK3CA | |
| SCHEMBL26998538 | 0.86 | ATR (0.38) | ATRATRIPROCK2PIK3R2ROCK1 | |
| SCHEMBL27000783 | 0.84 | ATR (0.48) | ATRATRIPROCK2 | |
| SCHEMBL26998294 | 0.83 | ATR (0.39) | ATRATRIPROCK2PIK3CAROCK1 | |
| SCHEMBL26998300 | 0.83 | ATR (0.39) | ATRATRIPROCK2PIK3CAROCK1 | |
| SCHEMBL27000875 | 0.83 | ATR (0.43) | ATRATRIPROCK2PIK3CAROCK1 | |
| SCHEMBL27000319 | 0.81 | ATR (0.64) | ATRATRIP | |
| SCHEMBL27000760 | 0.80 | PRKAB2 (0.39) | ATRATRIPROCK2PIK3R2 | |
| SCHEMBL26998091 | 0.80 | ROCK2 (0.43) | ATRATRIPROCK2 | |
| SCHEMBL27000337 | 0.78 | ATR (0.38) | ATRATRIPROCK2PIK3R2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11873291-B2 | Quinoline cGAS antagonist compounds | IMMUNESENSOR THERAPEUTICS, INC. (US) | 2024-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11873291-B2 | Quinoline cGAS antagonist compounds | CGAS, GLS2, GLS | ATR 277/4885ATRIP 734/4885ROCK2 1771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.