SCHEMBL27004160

SCHEMBL27004160

Cc1ccc(NC(=O)N2CCC(Cc3ccc4ccccc4c3)CC2)cc1

nearest known ligand 0.75

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FAAH O00519 9/20 0.75
MEN1 O00255 1/20 0.61
KMT2A Q03164 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
TDP1 Q9NUW8 1/20 0.54
TSHR P16473 1/20 0.52
CCR3 P51677 2/20 0.50
POLB P06746 1/20 0.50
ALOX15 P16050 1/20 0.50
CHRNA7 P36544 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19358917 0.89 SMN1; SMN2 (0.78) FAAHMEN1KMT2ASMN1; SMN2CCR3
SCHEMBL3598122 0.86 FAAH (1.00) FAAHMEN1KMT2ASMN1; SMN2TDP1
SCHEMBL27004157 0.84 FAAH (0.85) FAAHMEN1KMT2ASMN1; SMN2POLB
SCHEMBL830207 0.84 FAAH (0.74) FAAHMEN1KMT2ASMN1; SMN2CCR3
SCHEMBL27004161 0.81 FAAH (0.83) FAAHMEN1KMT2ASMN1; SMN2TDP1
SCHEMBL3639088 0.79 FAAH (0.60) FAAHMEN1KMT2ASMN1; SMN2CCR3
SCHEMBL3637699 0.79 FAAH (0.59) FAAHMEN1KMT2ASMN1; SMN2CCR3
SCHEMBL13902972 0.79 FAAH (0.54) FAAHMEN1KMT2ASMN1; SMN2CCR3
SCHEMBL1581690 0.78 ACHE (0.56) FAAHMEN1KMT2A
SCHEMBL29453749 0.78 ACHE (0.56) FAAHMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11873288-B2 Inhibitors for soluble epoxide hydrolase (sEH) and fatty acid amide hydrolase (FAAH) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-01-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11873288-B2 Inhibitors for soluble epoxide hydrolase (sEH) and fatty acid amide hydrolase (FAAH) FAAH, FAAH2, EPHX2 FAAH 1/4885MEN1 4059/4885KMT2A 1309/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.