Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.58 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.56 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | CTSC | P53634 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | STK17B | O94768 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | STS | P08842 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22643041 | 0.86 | ERN1 (0.54) | ERN1HSD17B2HDAC3HDAC4HDAC1 | |
| SCHEMBL2715947 | 0.80 | KDM4E (0.59) | ERN1PRKCZHSD17B2HDAC3HDAC4 | |
| SCHEMBL27005478 | 0.80 | PRKCZ (0.53) | ERN1PRKCZMAPTGAAKDM4E | |
| SCHEMBL6361017 | 0.79 | KDM4E (0.61) | ERN1HSD17B2HDAC3HDAC4HDAC1 | |
| SCHEMBL18832307 | 0.77 | HDAC6 (0.64) | ERN1HSD17B2HDAC6HSD17B1MAPT | |
| SCHEMBL12582258 | 0.77 | ERN1 (0.54) | ERN1HSD17B2HDAC3HDAC4HDAC1 | |
| SCHEMBL18832290 | 0.76 | PRF1 (0.54) | ERN1HDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL1784438 | 0.76 | ERN1 (0.56) | ERN1HSD17B2HDAC3HDAC4HDAC1 | |
| SCHEMBL12994882 | 0.75 | HSD17B1 (0.56) | ERN1HSD17B2HDAC3HDAC4HDAC1 | |
| SCHEMBL27761019 | 0.74 | GAA (0.53) | ERN1HSD17B2HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4306520-A1 | THIOPHENE COMPOUND AND APPLICATION THEREOF | Medshine Discovery Inc. (CN) | 2024-01-17 | — | — | EP | disclosed |