Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 1/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3602085 | 0.83 | MAPK14 (0.65) | PRKCZMAPK14MAPTKDM4EMEN1 | |
| SCHEMBL27005477 | 0.80 | ERN1 (0.58) | PRKCZMAPK14MAPTGAAKDM4E | |
| SCHEMBL27005480 | 0.79 | PRKCZ (0.51) | PRKCZMAPK14MAPTGAA | |
| SCHEMBL422050 | 0.75 | TRPM8 (0.53) | MAPTGAAKDM4EMEN1KMT2A | |
| SCHEMBL421731 | 0.74 | MAPK14 (0.46) | MAPK14MAPTGAAKDM4EMEN1 | |
| SCHEMBL27956364 | 0.72 | MAPK14 (0.52) | MAPK14MAPTGAATUBB4ATUBB | |
| SCHEMBL10109854 | 0.72 | PTPN2 (0.49) | MAPTGAAKDM4EMEN1KMT2A | |
| SCHEMBL423834 | 0.71 | MAPK14 (0.43) | MAPK14MAPTKDM4EMEN1KMT2A | |
| SCHEMBL12056211 | 0.71 | HSD17B2 (0.65) | PRKCZMAPTGAAKDM4EMEN1 | |
| SCHEMBL27005561 | 0.71 | HPGD (0.42) | MAPK14MAPTGAAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4306520-A1 | THIOPHENE COMPOUND AND APPLICATION THEREOF | Medshine Discovery Inc. (CN) | 2024-01-17 | — | — | EP | disclosed |