Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.80 |
| ▸ | ARG2 | P78540 | 4/20 | 0.50 |
| ▸ | ARG1 | P05089 | 3/20 | 0.50 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.48 |
| ▸ | NOS2 | P35228 | 6/20 | 0.44 |
| ▸ | NOS1 | P29475 | 4/20 | 0.44 |
| ▸ | NOS3 | P29474 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GRM8 | O00222 | 1/20 | 0.43 |
| ▸ | GRM6 | O15303 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL1476330 | 1.00 | GSR (0.80) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL28185340 | 1.00 | GSR (0.80) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL28241453 | 1.00 | GSR (0.80) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL20211608 | 1.00 | GSR (0.80) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL50314 | 1.00 | GSR (0.80) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL273455 | 1.00 | GSR (0.80) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL28193353 | 1.00 | GSR (0.80) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL28697152 | 1.00 | GSR (0.80) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL26606338 | 1.00 | GSR (0.80) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL4401871 | 0.98 | GSR (0.77) | GSRARG2ARG1RNPEPNOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120117936-A | Carbon dioxide-based low-carbon degradable coated controlled-release fertilizer and preparation method thereof | 北京市农林科学院 | 2025-06-10 | — | — | CN | claimed |
| CN-119775677-A | Antibacterial packaging material and preparation method thereof | 深圳中科长城技术有限公司 | 2025-04-08 | — | — | CN | claimed |
| US-20240360322-A1 | POWDER COATING COMPETITION | ARKEMA FRANCE (FR) | 2024-10-31 | — | — | US | claimed |
| CN-118286495-A | Fast-curing adhesive, and preparation method and application thereof | 诺一迈尔(山东)医学科技有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-118271558-A | Improved preparation technology of high-purity alkyl hydrazine polyurethane material | 东力（南通）化工有限公司 | 2024-07-02 | — | — | CN | claimed |
| EP-4373870-A1 | POWDER COATING COMPOSITION | ARKEMA FRANCE (FR) | 2024-05-29 | — | — | EP | claimed |
| CN-117693535-A | Powder coating composition | 阿科玛法国 | 2024-03-12 | — | — | CN | claimed |
| WO-2023123070-A1 | HIGH-PRESSURE-RESISTANT PIPELINE PLASTIC AND PREPARATION METHOD THEREFOR | 周菊青 | 2023-07-06 | — | — | WO | claimed |
| WO-2023123391-A1 | FLAME-RETARDANT KNITTED FABRIC AND PREPARATION METHOD THEREFOR | 管彦传 | 2023-07-06 | — | — | WO | claimed |
| CN-116284680-A | High-biobased content polymer controlled release material based on lysine isocyanate and coated controlled release fertilizer | 北京市农林科学院 | 2023-06-23 | — | — | CN | claimed |
| WO-2005005511-A1 | POROUS POLYURETHANE SHEET | HEPCE CHEM CO., LTD. (KR) | 2005-01-20 | — | — | WO | claimed |
| US-20050014858-A1 | Urethane polyol prepolymer, porous polyurethane sheet and method of preparing the same | HEPCE CHEM CO., LTD. (KR) | 2005-01-20 | — | — | US | claimed |
| US-20040058164-A1 | Bioabsorbable branched polymers containing units derived from dioxanone and medical/surgical devices manufactured therefrom | BENNETT STEVEN L (US) | 2004-03-25 | — | — | US | claimed |
| US-6362300-B1 | USING TERTIARY AMINE CATALYST | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2002-03-26 | — | — | US | claimed |
| CN-1064058-C | Method and device for regenerating unsaturated polyester resin waste | MIYANOBU CHEMICAL CO LTD (JP) | 2001-04-04 | — | — | CN | claimed |
| US-6207767-B1 | PROVIDING A POLYLACTONE STAR POLYMER, ENDCAPPING THE POLYMER WITH LYSINE DIISOCYANATE, CROSSLINKING THE ENDCAPPED POLYMER BY CONTACTING IT WITH A COMPOUND SELECTED FROM WATER, DIETHYLENE GLYCOL AND POLYETHYLENE GLYCOL | UNITED STATES SURGICAL CORPORATION | 2001-03-27 | — | — | US | claimed |
| US-6133395-A | ONE-COMPONENT MOISTURE CURABLE POLY(UREA)URETHANE COMPOSITIONS HAVING GOOD BONDING STRENGTH TO GLASS, METAL, PLASTIC SUBSTRATES WITHOUT PRIMER | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2000-10-17 | — | — | US | claimed |
| US-5578662-A | ENDCAPPED WITH LYSINE ISOCYANATE GROUPS; PROMOTES WOUND HEALING | UNITED STATES SURGICAL CORPORATION (US) | 1996-11-26 | — | — | US | claimed |
| CN-1117976-A | Method and device for regenerating unsaturated polyester resin waste | WAKAYAMA KEN (JP) | 1996-03-06 | — | — | CN | claimed |
| EP-0693294-A2 | Bioabsorbable branched polymers containing units derived from dioxanone and medical/surgical devices manufactured therefrom | United States Surgical Corporation (US) | 1996-01-24 | — | — | EP | claimed |