Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.80 |
| ▸ | ARG2 | P78540 | 4/20 | 0.50 |
| ▸ | ARG1 | P05089 | 3/20 | 0.50 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.48 |
| ▸ | NOS2 | P35228 | 6/20 | 0.44 |
| ▸ | NOS1 | P29475 | 4/20 | 0.44 |
| ▸ | NOS3 | P29474 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GRM8 | O00222 | 1/20 | 0.43 |
| ▸ | GRM6 | O15303 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL1476330 | 1.00 | GSR (0.80) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL28185340 | 1.00 | GSR (0.80) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL28241453 | 1.00 | GSR (0.80) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL20211608 | 1.00 | GSR (0.80) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL50314 | 1.00 | GSR (0.80) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL28193353 | 1.00 | GSR (0.80) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL28697152 | 1.00 | GSR (0.80) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL27006 | 1.00 | GSR (0.80) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL26606338 | 1.00 | GSR (0.80) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL4401871 | 0.98 | GSR (0.77) | GSRARG2ARG1RNPEPNOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3750 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026100731-A1 | COMPOSITION FOR OPTICAL MATERIAL, POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, OPTICAL MATERIAL, AND LENS | 三井化学株式会社 | 2026-05-15 | — | — | WO | claimed |
| CN-121108414-B | Raw material composition for preparing medium-high refractive index polyurethane optical material | 江苏视科新材料股份有限公司 | 2026-05-12 | — | — | CN | claimed |
| US-20260008903-A1 | POLYTHIOL COMPOSITION AND USE THEREOF | Efirm New Material Co., Ltd. (CN) | 2026-01-08 | — | — | US | claimed |
| EP-4651987-A1 | MICROCAPSULES FROM POLYLACTONE BASED PREPOLYMER | Firmenich SA (CH) | 2025-11-26 | — | — | EP | claimed |
| US-12421480-B2 | Core-shell capsules prepared with linear and cyclic aliphatic polyisocyanates | SYMRISE AG (DE) | 2025-09-23 | — | — | US | claimed |
| EP-4596599-A1 | POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, METHOD FOR PRODUCING SAME, AND OPTICAL MATERIAL | Mitsui Chemicals, Inc. (JP) | 2025-08-06 | — | — | EP | claimed |
| CN-120137368-A | Degradable material, preparation method and application thereof | 海信冰箱有限公司 | 2025-06-13 | — | — | CN | claimed |
| CN-118956124-B | Degradable composition for cup cover, preparation method of composition and cup cover | 磐安县鑫远新材料科技有限公司 | 2025-06-13 | — | — | CN | claimed |
| CN-120040703-A | Polythiol composition, polymerizable composition for optical product, and optical product | 益丰新材料股份有限公司 | 2025-05-27 | — | — | CN | claimed |
| CN-120004676-A | Metal complexing functional high-biobased polyurethane controlled release membrane material and application thereof | 北京市农林科学院 | 2025-05-16 | — | — | CN | claimed |
| US-20070160569-A1 | Medical adhesive and methods of tissue adhesion | PITTSBURGH, UNIVERSITY OF - OF THE COMMONWEALTH OF HIGHER EDUCATION | 2007-07-12 | — | — | US | claimed |
| US-6855792-B2 | Cross-linking agents and thermosetting paints | DEGUSSA AG (DE) | 2005-02-15 | — | — | US | claimed |
| US-6492482-B2 | WEAR AND CHEMICAL RESISTANCE | DEGUSS-HUELS AKTIENGESELLSCHAFT (DE) | 2002-12-10 | — | — | US | claimed |
| US-20020103286-A1 | Cross-linking agents and thermosetting paints | DEGUSSA AG (DE) | 2002-08-01 | — | — | US | claimed |
| US-6398669-B1 | URETHANE RESIN-, ACRYLIC RESIN-, OR EPOXY RESIN-BASED PAINT CONTAINING A POLYSILOXANE MODIFIED TO CONTAIN AT LEAST ONE HYDROXYL, CARBOXYL, ETHER OR ESTER GROUP; IMPROVES SURFACE SMOOTHNESS AND CONTAMINATION RESISTANCE | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2002-06-04 | — | — | US | claimed |
| US-6130307-A | POLY(THIO)URETHANES | MITSUBISHI GAS CHEMICAL CO., INC. (JP) | 2000-10-10 | — | — | US | claimed |
| EP-0579503-B1 | Radiation-curable, urethane-acrylate prepolymers and crosslinked polymers | ETHICON INC (US) | 1997-11-05 | — | — | EP | claimed |
| US-5674921-A | STEREOLITHOGRAPHICALLY FORMED MEDICAL DEVICE COMPRISING CROSSLINKED ACRYLATED POLYESTERURETHANE COPOLYMER HAVING HYDROLYZABLE POLYLACTONE GROUPS; WOUND CLOSURES | ETHICON, INC. (US) | 1997-10-07 | — | — | US | claimed |
| EP-0744422-A1 | POLYURETHANE RESIN | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-11-27 | — | — | EP | claimed |
| EP-0579503-A2 | Radiation-curable, urethane-acrylate prepolymers and crosslinked polymers | ETHICON INC. (US) | 1994-01-19 | — | — | EP | claimed |