Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.80 |
| ▸ | ARG2 | P78540 | 4/20 | 0.50 |
| ▸ | ARG1 | P05089 | 3/20 | 0.50 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.48 |
| ▸ | NOS2 | P35228 | 6/20 | 0.44 |
| ▸ | NOS1 | P29475 | 4/20 | 0.44 |
| ▸ | NOS3 | P29474 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GRM8 | O00222 | 1/20 | 0.43 |
| ▸ | GRM6 | O15303 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL1476330 | 1.00 | GSR (0.80) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL28185340 | 1.00 | GSR (0.80) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL28241453 | 1.00 | GSR (0.80) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL20211608 | 1.00 | GSR (0.80) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL273455 | 1.00 | GSR (0.80) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL28193353 | 1.00 | GSR (0.80) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL28697152 | 1.00 | GSR (0.80) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL27006 | 1.00 | GSR (0.80) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL26606338 | 1.00 | GSR (0.80) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL4401871 | 0.98 | GSR (0.77) | GSRARG2ARG1RNPEPNOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 24147 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118755343-B | Photo-curing organosilicon modified water-based acrylate coating and preparation method thereof | Changzhou University (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122080766-A | High-temperature thick coating prickly heat resistant primer and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122080848-A | Polyether amine modified polyimide binder and preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122079686-A | Surfactant-assisted multi-element inorganic nano mineral modified lignin-based coating material, preparation method thereof and coated fertilizer | — | 2026-05-26 | — | — | CN | claimed |
| EP-4745119-A1 | ISOCYANATE COMPOSITION | Hanwha Solutions Corporation (KR) | 2026-05-20 | — | — | EP | claimed |
| CN-119875072-B | Temperature-inhibiting type anti-cracking concrete waterproof agent and preparation method thereof | 中交第四航务工程局有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122060430-A | High-cohesion removable adhesive tape and preparation method thereof | 苏州世华新材料科技股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-119775741-B | Tough high-barrier functional film material and preparation method and application thereof | 江南大学 | 2026-05-19 | — | — | CN | claimed |
| CN-122037856-A | Degradable PUR hot melt adhesive based on composite bio-based polyol and continuous preparation method thereof | 浙江杰创新材料科技有限公司 | 2026-05-15 | — | — | CN | claimed |
| WO-2026100731-A1 | COMPOSITION FOR OPTICAL MATERIAL, POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, OPTICAL MATERIAL, AND LENS | 三井化学株式会社 | 2026-05-15 | — | — | WO | claimed |
| US-4726992-A | VERTICAL FERROMAGNETIC HEXAGONAL CRYSTALS IN A POLYCARBONATE POLYURETHANE BINDER | FUJI PHOTO FILM CO., LTD. (JP) | 1988-02-23 | — | — | US | claimed |
| US-4696991-A | Blocked polyisocyanurate | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1987-09-29 | — | — | US | claimed |
| US-4690987-A | Activation energy-curable resin composition | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1987-09-01 | — | — | US | claimed |
| US-4657817-A | POLYESTER URETHANE ACRYLATES HARDENED BY IRRADIATION; WEAR RESISTANCE | FUJI PHOTO FILM CO., LTD. (JP) | 1987-04-14 | — | — | US | claimed |
| EP-0214495-A2 | Plastisol composition, undercoating and blocked polyisocyanurate | MITSUBISHI KASEI VINYL COMPANY (JP) | 1987-03-18 | — | — | EP | claimed |
| US-4591545-A | Photosensitive image-forming material having a layer of photosensitive polyester modified with chain extender | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1986-05-27 | — | — | US | claimed |
| US-4388445-A | POLYMERIC BLEND | KANSAI PAINT CO., LTD. (JP) | 1983-06-14 | — | — | US | claimed |
| US-4221686-A | REACTING ACID-ISOCYANATE REACTION PRODUCT WITH ACID-EPOXIDE REACTION PRODUCT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-09-09 | — | — | US | claimed |
| US-4210713-A | HIDING POWER | NIPPON PAINT CO., LTD. (JP) | 1980-07-01 | — | — | US | claimed |
| US-4092172-A | Photocurable composition comprising a copolymer of a maleic acid monoester with an α-olefine | KANSAI PAINT CO., LTD. (JA) | 1978-05-30 | — | — | US | claimed |