Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 10/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | FYN | P06241 | 2/20 | 0.45 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9384083 | 0.79 | KMT2A (0.62) | CYP2A6ALDH1A1CYP3A4CYP1A2FYN | |
| SCHEMBL1991928 | 0.78 | KMT2A (0.59) | ALDH1A1KDM4ELMNATP53MAPT | |
| SCHEMBL21634194 | 0.78 | CYP2A6 (0.50) | CYP2A6ALDH1A1CYP3A4CYP1A2FYN | |
| SCHEMBL28227590 | 0.78 | CYP2A6 (0.50) | CYP2A6ALDH1A1CYP3A4CYP1A2FYN | |
| SCHEMBL2614253 | 0.78 | CYP2A6 (0.50) | CYP2A6ALDH1A1CYP3A4CYP1A2FYN | |
| SCHEMBL27843224 | 0.75 | CYP2A6 (0.47) | CYP2A6ALDH1A1CYP3A4CYP1A2FYN | |
| SCHEMBL27843225 | 0.75 | CYP2A6 (0.47) | CYP2A6ALDH1A1CYP3A4CYP1A2FYN | |
| SCHEMBL14405046 | 0.74 | CYP2A6 (0.54) | CYP2A6ALDH1A1CYP3A4CYP1A2FYN | |
| SCHEMBL6691985 | 0.74 | CYP2A6 (0.45) | CYP2A6ALDH1A1CYP3A4CYP1A2FYN | |
| SCHEMBL6677484 | 0.74 | ALDH1A1 (0.50) | CYP2A6ALDH1A1CYP3A4CYP1A2FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018119-A1 | CARBOXAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS | TRINEURO (KR) | 2024-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018119-A1 | CARBOXAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS | MAOA, DRD2, MAOB | CYP2A6 391/4885ALDH1A1 1214/4885CYP3A4 672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.