SCHEMBL27008249

SCHEMBL27008249

CC1(C(=O)NCCN2CCC(Cc3ccccc3)CC2)CC1

nearest known ligand 0.67

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 5/20 0.64
SLC6A3 Q01959 3/20 0.64
SLC6A4 P31645 2/20 0.61
PRMT6 Q96LA8 2/20 0.61
CARM1 Q86X55 1/20 0.61
CCR3 P51677 4/20 0.57
TMEM97 Q5BJF2 3/20 0.55
ALDH1A1 P00352 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23649319 0.83 SLC6A2 (0.74) SLC6A2SLC6A3SLC6A4PRMT6CARM1
SCHEMBL4853191 0.81 SLC6A2 (0.71) SLC6A2SLC6A3SLC6A4PRMT6CARM1
SCHEMBL24075739 0.80 SLC6A2 (0.70) SLC6A2SLC6A3SLC6A4PRMT6CARM1
SCHEMBL4852114 0.78 SLC6A2 (0.63) SLC6A2SLC6A3SLC6A4PRMT6CARM1
SCHEMBL18568473 0.77 SLC6A2 (0.72) SLC6A2SLC6A3SLC6A4CCR3TMEM97
SCHEMBL10145310 0.76 PRMT6 (1.00) PRMT6CARM1CCR3TMEM97
SCHEMBL313395 0.76 MEN1 (0.65) SLC6A2SLC6A3SLC6A4PRMT6CARM1
SCHEMBL27016196 0.75 SLC6A2 (0.67) SLC6A2SLC6A3SLC6A4PRMT6CARM1
Hydrochloric Acid SCHEMBL9869544 0.75 KCNH2 (0.65) SLC6A2SLC6A3SLC6A4PRMT6CARM1
SCHEMBL24076758 0.74 SLC6A2 (0.69) SLC6A2SLC6A3SLC6A4CCR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116057049-A Carboxamide derivatives and pharmaceutical composition for preventing or treating mental diseases containing the same as active ingredient 大邱庆北尖端医疗产业振兴财团 2023-05-02 CN claimed
US-20240018119-A1 CARBOXAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS TRINEURO (KR) 2024-01-18 US disclosed
US-20240018119-A1 CARBOXAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS TRINEURO (KR) 2024-01-18 US disclosed
US-20240018119-A1 CARBOXAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS TRINEURO (KR) 2024-01-18 US disclosed
CN-116057049-A Carboxamide derivatives and pharmaceutical composition for preventing or treating mental diseases containing the same as active ingredient 大邱庆北尖端医疗产业振兴财团 2023-05-02 CN disclosed
EP-4159725-A1 CARBOXAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS Daegu-Gyeongbuk Medical Innovation Foundation (KR) 2023-04-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240018119-A1 CARBOXAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS MAOA, DRD2, MAOB SLC6A2 4/4885SLC6A3 13/4885SLC6A4 23/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.