SCHEMBL27009145

SCHEMBL27009145

CC(=O)CCC(F)(F)C=O

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
LMNA P02545 1/20 0.35
SLC15A2 Q16348 1/20 0.35
ACHE P22303 1/20 0.34
FAAH O00519 8/20 0.32
CES1 P23141 5/20 0.31
CES2 O00748 2/20 0.31
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31
MAPT P10636 1/20 0.31
PAOX Q6QHF9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30416279 0.78 LMNA (0.38) ALDH1A1LMNASLC15A2MEN1CYP1A2
SCHEMBL6647762 0.74
SCHEMBL19859965 0.72
SCHEMBL26971253 0.71 ALDH1A1 (0.36) ALDH1A1LMNASLC15A2
SCHEMBL14213759 0.70 ALDH1A1 (0.45) ALDH1A1LMNASLC15A2ACHEFAAH
SCHEMBL1031370 0.69
SCHEMBL22310252 0.69 TSHR (0.52) ALDH1A1LMNAMEN1KMT2A
SCHEMBL20223162 0.68 ALDH1A1 (0.43) ALDH1A1LMNASLC15A2ACHEFAAH
SCHEMBL31016297 0.68 ALDH1A1 (0.56) ALDH1A1LMNASLC15A2ACHEPAOX
SCHEMBL22309119 0.67 TSHR (0.50) ALDH1A1LMNAFAAHMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240016946-A1 DRUG-LOADED MACROMOLECULE AND PREPARATION METHOD THEREFOR SHANGHAI SHENGDI PHARMACEUTICAL CO., LTD. (CN) 2024-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240016946-A1 DRUG-LOADED MACROMOLECULE AND PREPARATION METHOD THEREFOR MRPL38, MRPS27, MRPS18A ALDH1A1 2240/4885LMNA 1877/4885SLC15A2 216/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.