SCHEMBL14213759

SCHEMBL14213759

CC(=O)CCC(F)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.45
LMNA P02545 1/20 0.38
SLC15A2 Q16348 1/20 0.38
ACHE P22303 1/20 0.32
PAOX Q6QHF9 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
GAA P10253 1/20 0.31
TRPA1 O75762 1/20 0.30
FAAH O00519 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6647762 0.78
SCHEMBL19859965 0.76
SCHEMBL30775477 0.73 ALDH1A1 (0.39) ALDH1A1LMNASLC15A2
SCHEMBL20223162 0.72 ALDH1A1 (0.43) ALDH1A1LMNASLC15A2ACHEPAOX
SCHEMBL19699328 0.72 THRB (0.38) ALDH1A1LMNASLC15A2
SCHEMBL31016297 0.71 ALDH1A1 (0.56) ALDH1A1LMNASLC15A2ACHEPAOX
SCHEMBL14213756 0.70 ALDH1A1 (0.41) ALDH1A1LMNASLC15A2ACHEPAOX
SCHEMBL27009145 0.70 ALDH1A1 (0.41) ALDH1A1LMNASLC15A2ACHEPAOX
SCHEMBL26971247 0.70 LMNA (0.52) ALDH1A1LMNASLC15A2TDP1
SCHEMBL6801343 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8329344-B2 Fluorinated, acyclic carbonate derivatives; electrolytic double layer capacitor; excellent flame retardance, low temperature characteristics, withstand voltage, high solubility of an electrolyte salt; excellent compatibility with a hydrocarbon solvent DAIKIN INDUSTRIES, LTD. (JP) 2012-12-11 US disclosed