Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | TSHR | P16473 | 7/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 4/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24317829 | 0.93 | ALDH1A1 (0.57) | ALDH1A1TSHRCYP2D6POLBSMN1; SMN2 | |
| SCHEMBL27010324 | 0.90 | ALDH1A1 (0.61) | ALDH1A1TSHRCYP2D6POLBSMN1; SMN2 | |
| SCHEMBL24317329 | 0.88 | TSHR (0.48) | ALDH1A1TSHRCYP2D6CYP3A4POLB | |
| SCHEMBL24317919 | 0.86 | TSHR (0.57) | ALDH1A1TSHRCYP2D6CYP3A4POLB | |
| SCHEMBL27010252 | 0.86 | TSHR (0.60) | ALDH1A1TSHRCYP2D6POLBSMN1; SMN2 | |
| SCHEMBL27010254 | 0.86 | ALDH1A1 (0.54) | ALDH1A1TSHRCYP2D6CYP3A4POLB | |
| SCHEMBL26633868 | 0.84 | TSHR (0.55) | ALDH1A1TSHRCYP2D6CYP3A4POLB | |
| SCHEMBL26620053 | 0.84 | TSHR (0.55) | ALDH1A1TSHRCYP2D6CYP3A4POLB | |
| SCHEMBL27010257 | 0.84 | ALDH1A1 (0.52) | ALDH1A1TSHRCYP2D6CYP3A4POLB | |
| SCHEMBL26620054 | 0.83 | TSHR (0.53) | ALDH1A1TSHRCYP2D6CYP3A4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018118-A1 | TRICYCLIC COMPOUNDS TO DEGRADE NEOSUBSTRATES FOR MEDICAL THERAPY | C 4 Therapeutics, Inc. (US) | 2024-01-18 | — | — | US | disclosed |
| US-20240018118-A1 | TRICYCLIC COMPOUNDS TO DEGRADE NEOSUBSTRATES FOR MEDICAL THERAPY | C 4 Therapeutics, Inc. (US) | 2024-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018118-A1 | TRICYCLIC COMPOUNDS TO DEGRADE NEOSUBSTRATES FOR MEDICAL THERAPY | NFATC1, CTSS, MMP12 | ALDH1A1 2267/4885TSHR 2445/4885CYP2D6 3211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.