Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.63 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | EBP | Q15125 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27010694 | 0.85 | SLC18A3 (0.46) | SLC18A3SIGMAR1HRH4HRH3LTA4H | |
| SCHEMBL11463073 | 0.83 | SLC18A3 (0.71) | SLC18A3SIGMAR1HRH4HRH3OPRK1 | |
| SCHEMBL27010700 | 0.83 | KDM4E (0.52) | SLC18A3OPRK1OPRM1TSHRL3MBTL1 | |
| SCHEMBL11464581 | 0.80 | SLC18A3 (0.66) | SLC18A3SIGMAR1HRH4HRH3OPRK1 | |
| SCHEMBL27010674 | 0.79 | SLC18A3 (0.60) | SLC18A3SIGMAR1HRH4HRH3EBP | |
| SCHEMBL27010666 | 0.79 | SMN1; SMN2 (0.41) | SLC18A3HRH3OPRK1OPRM1OPRD1 | |
| SCHEMBL11748732 | 0.78 | SLC18A3 (0.67) | SLC18A3SIGMAR1HRH4HRH3OPRK1 | |
| SCHEMBL6391373 | 0.78 | SLC18A3 (1.00) | SLC18A3SIGMAR1HRH4HRH3EBP | |
| SCHEMBL6391371 | 0.78 | SLC18A3 (1.00) | SLC18A3SIGMAR1HRH4HRH3EBP | |
| SCHEMBL9433040 | 0.78 | SLC18A3 (1.00) | SLC18A3SIGMAR1HRH4HRH3EBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018118-A1 | TRICYCLIC COMPOUNDS TO DEGRADE NEOSUBSTRATES FOR MEDICAL THERAPY | C 4 Therapeutics, Inc. (US) | 2024-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018118-A1 | TRICYCLIC COMPOUNDS TO DEGRADE NEOSUBSTRATES FOR MEDICAL THERAPY | NFATC1, CTSS, MMP12 | SLC18A3 1846/4885SIGMAR1 3709/4885HRH4 2334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.