Hydrochloric Acid

Hydrochloric Acid

SCHEMBL270107

CC=CC(=O)OCC(O)C[N+](C)(C)C.[Cl-]

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 known ✓ P11229 3/20 0.33
CHRM2 known ✓ P08172 2/20 0.33
CHRM3 known ✓ P20309 2/20 0.32
MAPT P10636 5/20 0.42
SLC22A16 Q86VW1 1/20 0.38
SMN1; SMN2 Q16637 3/20 0.36
BLM P54132 2/20 0.36
GALR3 O60755 1/20 0.36
LMNA P02545 3/20 0.35
TSHR P16473 3/20 0.33
CHRM4 P08173 2/20 0.33
GSTP1 P09211 1/20 0.33
TBXA2R P21731 1/20 0.33
CHRM5 P08912 2/20 0.32
CYP2C9 P11712 1/20 0.32
HCAR2 Q8TDS4 1/20 0.31
ATM Q13315 1/20 0.31
USP2 O75604 1/20 0.30
ALDH1A1 P00352 1/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL758620 0.98 MAPT (0.39) MAPTSLC22A16SMN1; SMN2BLMGALR3
Bromide SCHEMBL11520163 0.96 MAPT (0.38) MAPTSLC22A16SMN1; SMN2BLMGALR3
Sulfuric Acid SCHEMBL11519852 0.91 MAPT (0.35) MAPTSLC22A16SMN1; SMN2BLMGALR3
Phosphoric Acid SCHEMBL8763242 0.91 MAPT (0.35) MAPTSLC22A16SMN1; SMN2BLMGALR3
Hydrochloric Acid SCHEMBL10839320 0.88 MAPT (0.34) MAPTSLC22A16SMN1; SMN2TSHRUSP2
Hydrochloric Acid SCHEMBL8777402 0.86 HCAR2 (0.34) MAPTTSHRGSTP1HCAR2ATM
SCHEMBL20335453 0.86 TSHR (0.39) MAPTSMN1; SMN2LMNATSHRGSTP1
SCHEMBL23581952 0.81 TSHR (0.35) MAPTSMN1; SMN2TSHRGSTP1HCAR2
SCHEMBL650096 0.81 HCAR2 (0.36) MAPTSMN1; SMN2LMNATSHRGSTP1
SCHEMBL2868662 0.81 KDM4E (0.43) LMNATSHRGSTP1HCAR2ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 490 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230279471-A1 METHODS FOR SEPARATING AND DETECTING DOUBLE-STRANDED AND SINGLE-STRANDED RIBONUCLEIC ACID (RNA) REVVITY HEALTH SCIENCES, INC. 2023-09-07 US claimed
WO-2023164258-A1 METHODS FOR SEPARATING AND DETECTING DOUBLE-STRANDED AND SINGLE-STRANDED RIBONUCLEIC ACID (RNA) PERKINELMER HEALTH SCIENCES, INC. (US) 2023-08-31 WO claimed
US-10113099-B2 High pressure high temperature (HPHT) aqueous drilling mud composition and process for preparing the same ISP INVESTMENTS LLC (US) 2018-10-30 US claimed
US-20150368538-A1 A NOVEL HIGH PRESSURE HIGH TEMPERATURE (HPHT) AQUEOUS DRILLING MUD COMPOSITION AND PROCESS FOR PREPARING THE SAME ISP INVESTMENTS INC. (US) 2015-12-24 US claimed
WO-2014133824-A1 A NOVEL HIGH PRESSURE HIGH TEMPERATURE (HPHT) AQUEOUS DRILLING MUD COMPOSITION AND PROCESS FOR PREPARING THE SAME ISP INVESTMENTS INC. (US) 2014-09-04 WO claimed
EP-1173878-B1 PROBES FOR A GAS PHASE ION SPECTROMETER BIO RAD LABORATORIES (US) 2011-04-06 EP claimed
US-7582684-B2 Macroporous ion exchange resins 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-09-01 US claimed
US-7205156-B2 Probes for a gas phase ion spectrometer BIO-RAD LABORATORIES, INC. (US) 2007-04-17 US claimed
US-6897072-B1 Probes for a gas phase ion spectrometer CIPHERGEN BIOSYSTEMS, INC. (US) 2005-05-24 US claimed
US-6783838-B2 Coated film laminate having an ionic surface 3M INNOVATIVE PROPERTIES COMPANY 2004-08-31 US claimed
US-5645968-A Cationic Toner processes XEROX CORPORATION (US) 1997-07-08 US claimed
EP-0371821-B1 A process for the production of substituted acryloyloxyhydroxypropyltrialkylammonium chloride RHONE POULENC SPEC CHIM (US) 1994-05-25 EP claimed
EP-0591233-A1 POLYMER COATINGS BIOINTERACTIONS LIMITED (GB) 1994-04-13 EP claimed
WO-1993000391-A1 POLYMER COATINGS BIOINTERACTIONS LIMITED (GB) 1993-01-07 WO claimed
US-5132383-A Salt formation by reacting halohydroxypropyl methacrylate mixtures with trialkylamine; addition polymerization; flocculants POLYPURE, INC. (US) 1992-07-21 US claimed
US-5008444-A Reacting halohydroxypropyl (meth)acrylate with trialkylamine in nonsolvent for quaternary salt POLYPURE, INC. (US) 1991-04-16 US claimed
EP-0371822-A1 Copolymers of 3-methacryloyloxy-2-hydroxypropyl trimethylammonium chloride monomer and vinyl monomer S. N. F. (FR) 1990-06-06 EP claimed
EP-0371821-A1 A process for the production of substituted acryloyloxyhydroxypropyltrialkylammonium chloride RHONE-POULENC SPECIALTY CHEMICALS CO. (US) 1990-06-06 EP claimed
US-4426483-A CROSSLINKED GRAFT POLYMERS OF UNSATURATED MONOMERS HERCULES INCORPORATED (US) 1984-01-17 US claimed
US-4353818-A GRAFT CATIONIC COPOLYMERS; FILLERS FOR PAPER HERCULES INCORPORATED (US) 1982-10-12 US claimed