Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL270107 | 0.86 | MAPT (0.42) | HCAR2ATMMAPTGSTP1TSHR | |
| SCHEMBL758620 | 0.84 | MAPT (0.39) | HCAR2ATMMAPTGSTP1TSHR | |
| Bromide SCHEMBL11520163 | 0.83 | MAPT (0.38) | HCAR2ATMMAPTGSTP1TSHR | |
| SCHEMBL20335453 | 0.80 | TSHR (0.39) | HCAR2ATMMAPTGSTP1TSHR | |
| SCHEMBL650097 | 0.79 | HCAR2 (0.36) | HCAR2ATMMAPTGSTP1TSHR | |
| SCHEMBL650096 | 0.79 | HCAR2 (0.36) | HCAR2ATMMAPTGSTP1TSHR | |
| Sulfuric Acid SCHEMBL11519852 | 0.79 | MAPT (0.35) | MAPTGSTP1TSHR | |
| Phosphoric Acid SCHEMBL8763242 | 0.79 | MAPT (0.35) | MAPTGSTP1TSHR | |
| Hydrochloric Acid SCHEMBL11522455 | 0.77 | ATM (0.39) | HCAR2PSMD14PLA2G1BMMP2RAD52 | |
| Hydrochloric Acid SCHEMBL11521883 | 0.77 | PLA2G1B (0.44) | HCAR2PSMD14PLA2G1BMMP2RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107190562-B | Method for producing paper | 索马龙株式会社 | 2022-01-11 | — | — | CN | disclosed |
| CN-106868934-B | Method for producing paper and retention aid kit | 索马龙株式会社 | 2021-06-29 | — | — | CN | disclosed |
| EP-0812956-A1 | HIGH PERFORMANCE PAPER AND PROCESS FOR PRODUCING THE SAME | Oji Paper Co., Ltd. (JP) | 1997-12-17 | — | — | EP | disclosed |
| US-5180473-A | Cationic Polymer Retention Aid | MITSUI-CYANAMID, LTD. (JP) | 1993-01-19 | — | — | US | disclosed |
| US-4152307-A | FLOCCULANTS | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 1979-05-01 | — | — | US | disclosed |