SCHEMBL270135

SCHEMBL270135

CC(=O)CCC(C)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 1/20 0.50
ALDH1A1 P00352 1/20 0.48
TRPA1 O75762 3/20 0.47
TAAR1 Q96RJ0 3/20 0.47
MTNR1A P48039 1/20 0.46
MTNR1B P49286 1/20 0.46
ALOX5 P09917 1/20 0.43
AOC3 Q16853 1/20 0.42
FFAR1 O14842 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8673121 0.86 RIPK1 (0.52) RIPK1ALDH1A1TRPA1TAAR1FFAR1
SCHEMBL242853 0.86 RIPK1 (0.52) RIPK1ALDH1A1TRPA1TAAR1FFAR1
SCHEMBL10042378 0.86 RIPK1 (0.52) RIPK1ALDH1A1TRPA1TAAR1FFAR1
SCHEMBL6718333 0.84 RIPK1 (0.50) RIPK1TRPA1TAAR1MTNR1AMTNR1B
Acetic Acid SCHEMBL10839331 0.84 RIPK1 (0.50) RIPK1TRPA1TAAR1MTNR1AMTNR1B
Hydrochloric Acid SCHEMBL5743278 0.84 RIPK1 (0.50) RIPK1ALDH1A1TRPA1TAAR1FFAR1
SCHEMBL11543107 0.83 MTNR1A (0.58) ALDH1A1MTNR1AMTNR1B
SCHEMBL8423195 0.82 RIPK1 (0.48) RIPK1ALDH1A1TRPA1TAAR1ALOX5
SCHEMBL2091300 0.82 TAAR1 (0.50) RIPK1TRPA1TAAR1ALOX5AOC3
SCHEMBL5743275 0.82 RIPK1 (0.48) RIPK1ALDH1A1TRPA1TAAR1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2291418-B1 PREPARATION OF EXO-OLEFIN TERMINATED POLYOLEFINS VIA QUENCHING WITH ALKOXYSILANES THE UNIV OF SOUTHERN MISSISSIPPI (US) 2020-06-17 EP disclosed
EP-2303939-B1 COPOLYMERS MADE WITH ALLYL-TERMINATED POLYOLEFINS AND UNSATURATED ACIDIC REAGENTS, DISPERSANTS USING SAME, AND METHODS OF MAKING SAME CHEVRON ORONITE CO (US) 2017-04-05 EP disclosed
US-20160032041-A1 COPOLYMERS MADE WITH ALLYL-TERMINATED POLYOLEFINS AND UNSATURATED ACIDIC REAGENTS, DISPERSANTS USING SAME, AND METHODS OF MAKING SAME CHEVRON ORONITE CO (US) 2016-02-04 US disclosed
EP-1489109-B1 Living and quasiliving cationic telechelic polymers quenched by N-substituted pyrrole and methods for their preparation CHEVRON ORONITE CO (US) 2015-08-19 EP disclosed
US-8895672-B2 Production of vinylidene-terminated and sulfide-terminated telechelic polyolefins via quenching with disulfides CHEVRON ORONITE COMPANY LLC (US) 2014-11-25 US disclosed
US-20130345104-A1 POLYISOBUTENYL SULFONATES HAVING LOW POLYDISPERSITY CHEVRON ORONITE COMPANY LLC (US) 2013-12-26 US disclosed
US-20130331525-A1 PRODUCTION OF VINYLIDENE-TERMINATED AND SULFIDE-TERMINATED TELECHELIC POLYOLEFINS VIA QUENCHING WITH DISULFIDES CHEVRON ORONITE COMPANY LLC (US) 2013-12-12 US disclosed
US-8575279-B2 Method for preparation of polyolefins containing exo-olefin chain ends CHEVRON ORONITE COMPANY LLC (US) 2013-11-05 US disclosed
US-8507641-B2 Production of vinylidene-terminated and sulfide-terminated telechelic polyolefins via quenching with disulfides CHEVRON ORONITE COMPANY LLC (US) 2013-08-13 US disclosed
US-20130158207-A1 PRODUCTION OF VINYLIDENE-TERMINATED AND SULFIDE-TERMINATED TELECHELIC POLYOLEFINS VIA QUENCHING WITH DISULFIDES CHEVRON ORONITE COMPANY LLC (US) 2013-06-20 US disclosed
EP-1786843-A2 METHOD FOR PREPARATION OF POLYOLEFINS CONTAINING EXO-OLEFIN CHAIN ENDS Chevron Oronite Company LLC (US) 2007-05-23 EP disclosed
WO-2006023742-A2 METHOD FOR PREPARATION OF POLYOLEFINS CONTAINING EXO-OLEFIN CHAIN ENDS CHEVRON ORONITE COMPANY LLC (US) 2006-03-02 WO disclosed
US-20060041083-A1 quenching cationic quasi-living polyolefin polymer system with pyrroles, imidazoles; lubricating oil additives CHEVRON ORONITE COMPANY LLC 2006-02-23 US disclosed
US-20050282972-A1 Process for preparing terminally functionalized living and quasiliving cationic telechelic polymers STOKES CASEY D 2005-12-22 US disclosed
US-6969744-B2 Living and quasiliving cationic telechelic polymers quenched by N-substituted pyrrole and methods for their preparation UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2005-11-29 US disclosed
US-20040260033-A1 Living and quasiliving cationic telechelic polymers quenched by N-substituted pyrrole and methods for their preparation UNIVERSITY OF SOUTHERN MISSISSIPPI 2004-12-23 US disclosed
EP-1489109-A2 Living and quasiliving cationic telechelic polymers quenched by N-substituted pyrrole and methods for their preparation Chevron Oronite Company LLC (US) 2004-12-22 EP disclosed
CN-1056602-C Esters and amides as PLA2 inhibitors FUJISAWA PHARMACEUTICAL CO (JP) 2000-09-20 CN disclosed
CN-1197450-A Esters and amides as phospholipase A2 inhibitors FUJISAWA PHARMACEUTICAL CO (JP) 1998-10-28 CN disclosed
EP-0009540-B1 FRAGRANCE COMPOSITIONS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1983-03-02 EP disclosed