Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 7/20 | 0.65 |
| ▸ | NAALAD2 | Q9Y3Q0 | 4/20 | 0.60 |
| ▸ | JAK2 | O60674 | 1/20 | 0.56 |
| ▸ | NQO1 | P15559 | 1/20 | 0.56 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.55 |
| ▸ | TTR | P02766 | 1/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | MIF | P14174 | 1/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20809317 | 0.93 | FTO (0.70) | FTONAALAD2JAK2NQO1NR1H2 | |
| SCHEMBL15045059 | 0.92 | FTO (0.61) | FTONAALAD2JAK2NQO1NR1H2 | |
| SCHEMBL8893358 | 0.92 | NAALAD2 (0.62) | FTONAALAD2JAK2NQO1NR1H2 | |
| SCHEMBL22863319 | 0.91 | NAALAD2 (0.63) | FTONAALAD2JAK2NQO1NR1H2 | |
| SCHEMBL29353892 | 0.90 | FTO (0.63) | FTONAALAD2JAK2NQO1NR1H2 | |
| SCHEMBL991216 | 0.90 | FTO (0.63) | FTONAALAD2JAK2NQO1NR1H2 | |
| SCHEMBL15744221 | 0.89 | FTO (0.64) | FTONAALAD2JAK2NQO1NR1H2 | |
| SCHEMBL16602999 | 0.88 | NAALAD2 (0.60) | FTONAALAD2JAK2NQO1NR1H2 | |
| SCHEMBL27016019 | 0.87 | TTR (0.64) | FTONAALAD2JAK2NQO1NR1H2 | |
| SCHEMBL17956697 | 0.87 | FTO (0.69) | FTONAALAD2JAK2NQO1NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9890197-B2 | RHAMM binding peptides | LONDON HEALTH SCIENCES CENTRE RESEARCH INC. (CA) | 2018-02-13 | — | — | US | disclosed |
| EP-3168226-A2 | RHAMM BINDING PEPTIDES | London Health Sciences Centre Research Inc. (CA) | 2017-05-17 | — | — | EP | disclosed |