Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.54 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.54 |
| ▸ | KLK7 | P49862 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | FNTA | P49354 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2698758 | 0.84 | KMT2A (0.62) | SMN1; SMN2MEN1KMT2ALMNAHTT | |
| SCHEMBL6819134 | 0.84 | MAPT (0.49) | ALDH1A1MEN1KMT2ALMNAHTT | |
| SCHEMBL2701806 | 0.84 | KMT2A (0.60) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL2700751 | 0.84 | RNF4 (0.49) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL2702309 | 0.84 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL20942366 | 0.83 | RNF4 (0.67) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| Phenyl 4-Fluorophenylcarbamate SCHEMBL1892132 | 0.80 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL20620003 | 0.79 | MEN1 (0.71) | ALDH1A1SMN1; SMN2KLK7MEN1KMT2A | |
| Phenyl 4-Fluorophenylcarbamate SCHEMBL27580166 | 0.79 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL680052 | 0.78 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2KLK7MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120108592-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE OF SALICYLANILIDES FOR TREATMENT OF HEPATITIS VIRUSES | ROMARK LABORATORIES, L.C. | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108592-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE OF SALICYLANILIDES FOR TREATMENT OF HEPATITIS VIRUSES | PYGL, GYS2, GLS2 | ALDH1A1 533/4885SMN1; SMN2 3414/4885CXCR1 4842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.