SCHEMBL2702829

SCHEMBL2702829

CC=CCCc1cc[c]cc1

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR52 Q9Y2T5 5/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9457786 1.00 GPR52 (0.35) GPR52
SCHEMBL27417731 0.88 CBS (0.32)
SCHEMBL25306764 0.81 KCNH2 (0.34) GPR52
SCHEMBL27430275 0.81 KCNH2 (0.37) GPR52
SCHEMBL9457648 0.78 GPR52 (0.33) GPR52
SCHEMBL9457643 0.78 GPR52 (0.33) GPR52
SCHEMBL27544085 0.78 KCNH2 (0.42)
SCHEMBL10009929 0.77 HRH3 (0.43) GPR52
SCHEMBL448516 0.77 GPR52 (0.55) GPR52
SCHEMBL93627 0.77 MAOB (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023137133-A2 PROCESS FOR THE SELECTIVE CATALYTIC HYDROGENATION OF DIENONES BASF SE (DE) 2023-07-20 WO disclosed
CN-107548384-B Gypsum-containing composition 巴斯夫欧洲公司 2020-06-02 CN disclosed
CN-102850336-A DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZ0 [B] THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS OTSUKA PHARMA CO LTD 2013-01-02 CN disclosed
CN-102702182-A Derivatives of 4-piperazin-1-yl-4-benzo[b]thiophene suitable for the treatment of cns disorders OTSUKA PHARMA CO LTD 2012-10-03 CN disclosed
CN-102558140-A Derivatives of 4-piperazin-1-1-yl-4-benzo [b] thiophene suitable for the treatment of cns disorders OTSUKA PHARMA CO LTD 2012-07-11 CN disclosed
EP-2287161-B1 Derivatives of 4-piperazin-1-yl-4-benzo[b]thiophene suitable for the treatment of CNS disorders OTSUKA PHARMA CO LTD (JP) 2012-05-09 EP disclosed
CN-101258147-A 4-piperazin-1-yl-4-benzo [ B ] thiophene derivatives for the treatment of CNS disorders OTSUKA PHARMA CO LTD (JP) 2008-09-03 CN disclosed
EP-1919907-A2 HETEROCYCLIC COMPOUND OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2008-05-14 EP disclosed
CN-100350968-C Modification of feeding behavior IMP COLLEGE INNOVATIONS LTD (GB) 2007-11-28 CN disclosed
WO-2007026959-A2 DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZ0 [B] THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-03-08 WO disclosed
CN-1596119-A Modification of feeding behavior IMP COLLEGE INNOVATIONS LTD (GB) 2005-03-16 CN disclosed
CN-1168711-C Reversible aqueous pH sensitive lipidizing reagents, compositions and methods of use �ϼ��������Ǵ�ѧ 2004-09-29 CN disclosed
CN-1114602-C Ketone derivatives and medicinal use thereof TORAY INDUSTRIES (JP) 2003-07-16 CN disclosed
CN-1350519-A Reversible aqueous pH Sensitive lipidizing reagents, compositions and methods of use UNIV SOUTHERN CALIFORNIA (US) 2002-05-22 CN disclosed
CN-1070487-C Hexahydronaphthalene ester derivatives, their preparation and their therapeutic uses SANKYO CO (JP) 2001-09-05 CN disclosed
CN-1242771-A Ketone derivatives and medicinal use thereof TORAY INDUSTRIES (JP) 2000-01-26 CN disclosed
US-5238602-A Electrooptical cells HOFFMANN LA ROCHE INC. (US) 1993-08-24 US disclosed