SCHEMBL27028451

SCHEMBL27028451

O=C(NC1CCC(O)CC1)[C@@H]1C[C@H]1COCc1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MFN2 O95140 1/20 0.67
ALDH1A1 P00352 3/20 0.45
GAA P10253 1/20 0.45
HPGD P15428 1/20 0.45
BRD4 O60885 1/20 0.43
TSHR P16473 1/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
CPB1 P15086 1/20 0.42
SGMS2 Q8NHU3 1/20 0.42
EPHX2 P34913 2/20 0.42
EPHX1 P07099 1/20 0.41
SIGMAR1 Q99720 1/20 0.40
FFAR4 Q5NUL3 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27245325 1.00 MFN2 (0.67) MFN2ALDH1A1GAAHPGDBRD4
SCHEMBL22315339 0.82 MFN2 (0.86) MFN2ALDH1A1HPGDTSHRMEN1
SCHEMBL22289758 0.80 MFN2 (1.00) MFN2ALDH1A1HPGDTSHRMEN1
SCHEMBL22620161 0.80 MFN2 (1.00) MFN2ALDH1A1HPGDTSHRMEN1
SCHEMBL27245327 0.80 MFN2 (1.00) MFN2ALDH1A1HPGDTSHRMEN1
SCHEMBL27245326 0.80 MFN2 (1.00) MFN2ALDH1A1HPGDTSHRMEN1
SCHEMBL27245324 0.79 MFN2 (0.65) MFN2ALDH1A1GAAHPGDBRD4
SCHEMBL27245328 0.79 MFN2 (0.65) MFN2ALDH1A1GAAHPGDBRD4
SCHEMBL29188003 0.76 FFAR4 (0.57) ALDH1A1TSHRFFAR4
SCHEMBL17391191 0.76 FFAR4 (0.57) ALDH1A1TSHRFFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240199534-A1 CYCLOPROPANE ANALOGUES OF N-(TRANS-4-HYDROXYCYCLOHEXYL)-6-PHENYLHEXANAMIDE AND RELATED COMPOUNDS DORN, GERALD W., II, DR. 2024-06-20 US disclosed
EP-4308540-A1 CYCLOPROPANE ANALOGUES OF N-(TRANS-4-HYDROXYCYCLOHEXYL)-6-PHENYLHEXANAMIDE AND RELATED COMPOUNDS Mitochondria Emotion, Inc. (US) 2024-01-24 EP disclosed
CN-117377652-A Cyclopropane analogues of N- (trans-4-hydroxycyclohexyl) -6-phenylhexanamide and related compounds 线粒体情感状态公司 2024-01-09 CN disclosed
WO-2022198139-A1 CYCLOPROPANE ANALOGUES OF N-(TRANS-4-HYDROXYCYCLOHEXYL)-6-PHENYLHEXANAMIDE AND RELATED COMPOUNDS MITOCHONDRIA EMOTION, INC. (US) 2022-09-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240199534-A1 CYCLOPROPANE ANALOGUES OF N-(TRANS-4-HYDROXYCYCLOHEXYL)-6-PHENYLHEXANAMIDE AND RELATED COMPOUNDS HAGH, HADHA, NLN MFN2 135/4885ALDH1A1 884/4885GAA 500/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.